Product Name: T-Butylamine
Chemical Name: tert-Butylamine
CAS Number: 75-64-9
Synonyms: 2-Methyl-2-propanamine; tert-Butanamine
Recommended Uses: Intermediate for organic synthesis, pharmaceuticals, agrochemicals
Manufacturer Information: Check supplier label for current factory contact, address, phone, emergency contact
Emergency Phone Number: Provided by manufacturer or industrial safety setup
Relevant Identifiers: UN 2077, EC No. 200-889-9, RTECS: EO1575000, CHEMTREC 1-800-424-9300
Hazard Class: Flammable liquid (Category 2), Acute Toxicity (Category 3, inhalation, oral), Skin Corrosion/Irritation (Category 1B), Eye Damage/Irritation (Category 1)
Signal Word: Danger
Hazard Statement: Highly flammable liquid and vapor, toxic if inhaled or swallowed, causes severe skin burns and eye damage
Precautionary Statement: Avoid breathing vapors, keep away from heat, sparks, open flames, wear protective gloves, eye protection, wash thoroughly after handling
Pictograms: Flame, Corrosion, Skull and crossbones
Potential Effects: Respiratory irritation, skin blistering, vision damage, systemic toxicity
Chemical Identity: T-Butylamine
Concentration: 98% or higher
CAS Number: 75-64-9
Molecular Formula: C4H11N
Impurities: Water, trace amines, less than 1%
Stabilizers or Additives: None in pure laboratory or industrial form
Inhalation: Move to fresh air, support breathing, seek immediate medical attention
Skin Contact: Flush with water for at least 15 minutes, remove contaminated clothing, seek medical help
Eye Contact: Rinse cautiously with water for several minutes, remove contact lenses if present and easy, continue rinsing and see a physician
Ingestion: Rinse mouth, do not induce vomiting, get emergency medical help quickly
General Advice: Exposed persons may require medical observation for up to 48 hours because symptoms can be delayed
Physician Notes: Treat respiratorily or symptomatically, support vital functions if required
Suitable Extinguishing Media: Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide
Unsuitable Media: Water jet
Specific Hazards: Produces toxic vapors of nitrogen oxides and carbon oxides, burns very easily, vapor/air mixtures can explode
Protective Equipment: Wear full protective gear and positive pressure self-contained breathing apparatus
Special Precautions: Approach fire from upwind, move containers if safe, use caution with runoff as water may spread contamination
Firefighting Techniques: Cool containers with water spray if exposed to flames, avoid breathing vapors
Personal Precautions: Evacuate unnecessary personnel, use proper PPE including gloves, goggles, and chemical resistant clothing
Environmental Precautions: Prevent entry into sewers, ground, or waterways, alert fire brigade about significant spill
Methods for Clean Up: Use non-sparking tools, absorb with inert materials like vermiculite or sand, ventilate area, secure leak if possible
Disposal: Gather spilled material in closed, labeled containers for local disposal rules
Decontamination: Wash spill area thoroughly after clean-up, avoid secondary contamination
Handling: Work in a chemical fume hood, keep away from heat, sparks, open flames, avoid inhaling vapors or getting on skin and eyes, use grounded equipment
Storage Conditions: Store tightly sealed in a cool, well-ventilated place, away from incompatible materials like oxidizers and acids, separate from food and drink
Storage Temperature: Typically room temperature, avoid freezing or excessive heat
Incompatible Materials: Strong oxidizing agents, acids, acid chlorides, acid anhydrides
Occupational Exposure Limits: ACGIH TLV: 5 ppm (skin), OSHA PEL not established
Engineering Controls: Use local exhaust ventilation, safety showers, eyewash stations
Personal Protection: NIOSH/MSHA-approved respirator, chemical splash goggles, flame-resistant lab coat, gloves resistant to amines (nitrile or neoprene), closed-toe shoes
Hygiene Measures: Keep away from food, wash hands and face before eating, clean clothing regularly
Appearance: Clear, colorless to pale yellow liquid
Odor: Strong ammonia-like smell
Odor Threshold: Detectable at very low concentrations
pH: Basic in aqueous solution
Melting Point: -20°C
Boiling Point: 44°C
Flash Point: -14°C (closed cup)
Evaporation Rate: High
Flammability: Highly flammable
Vapor Pressure: 370 mmHg at 20°C
Vapor Density: 2.01 (air = 1)
Relative Density: 0.74 (water = 1)
Solubility: Miscible with water, alcohol, ether
Auto-ignition Temperature: 385°C
Decomposition Temperature: Data not widely reported
Partition Coefficient (n-octanol/water): ~0.84
Viscosity: Low
Chemical Stability: Stable under normal conditions with proper storage
Reactivity: Reacts violently with oxidizers, releases heat with acids and acid chlorides
Hazardous Reactions: Can form explosive mixtures with air, emits nitrogen oxides and carbon oxides when heated
Conditions to Avoid: Open flame, heat, sparks, electrostatic discharge
Incompatible Materials: Acids, oxidizing agents, acid chlorides, acid anhydrides
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide, nitrogen oxides, irritating organic fumes
Acute Toxicity: LD50 Oral (rat): 320 mg/kg; LC50 Inhalation (rat): 5860 mg/m3 (4h load-case); LD50 Dermal: not well reported
Routes of Exposure: Inhalation, ingestion, skin and eye contact
Effects on Health: Causes burns to skin and eyes, respiratory tract irritation, headache, coughing, dizziness, nausea, possible lung edema, central nervous system effects
Chronic Effects: Prolonged or repeated exposure may lead to dermatitis, respiratory sensitization
Carcinogenicity: Not classified as carcinogen
Mutagenicity/Teratogenicity: Not enough studies for classification
Ecotoxicity: Toxic to aquatic life in moderate concentrations; Fish LC50 (Leuciscus idus): 137 mg/L (96h), Daphnia EC50: 98 mg/L (48h)
Persistence and Degradability: Biodegradable under aerobic conditions; breakdown mostly in soil and water
Bioaccumulative Potential: Low, partition coefficient suggests limited risk
Mobility in Soil: Significant, due to water solubility
Other Adverse Effects: Can cause local pH shift and ammonia smell contamination in waterways
Waste Handling: Dump only in accordance with local, regional, national, and international laws
Recommended Disposal Method: Burn in chemical incinerator with afterburner and scrubber, consult licensed disposal companies
Contaminated Packaging: Dispose as hazardous waste; do not reuse
Precautions: Avoid release to the environment during disposal, protect water courses and drainage
UN Number: UN 2077
Shipping Name: tert-Butylamine
Hazard Class: 3 (Flammable liquid)
Packing Group: II
Labels: Flammable liquid, corrosive
Marine Pollutant: No
Special Precautions: Keep containers upright and secured, avoid excessive movement and dropping, ensure vehicle ventilation on road
OSHA: Classified hazardous by OSHA Hazard Communication Standard
TSCA: Listed in the US Toxic Substances Control Act Inventory
SARA Title III: Subject to reporting under SARA 302, SARA 311/312 (acute, fire), no SARA 313 chemicals
REACH: Registered substance in European Union; consult supplier on current status
WHMIS Classification (Canada): Class B2 (Flammable Liquid); Class E (Corrosive)
Other Regulations: Subject to local and international transport and export controls, restricted for use in some consumer applications
