Nanjing Finechem Holding Co.,Limited
Knowledge


Material Safety Data Sheet (MSDS) – Phenethylamine

Identification

Product Name: Phenethylamine
Chemical Formula: C8H11N
Synonyms: β-Phenylethylamine, Benzeneethanamine
CAS Number: 64-04-0
Recommended Use: Intermediate for chemical synthesis, research applications
Manufacturer: [Name and Address]
Emergency Contact: [Phone number]

Hazard Identification

Classification: Acute Toxicity (Oral, Dermal, Inhalation); Skin Corrosion/Irritation; Eye Damage/Irritation
Signal Word: Danger
Hazard Statements: May cause burns to skin and eyes; Harmful if swallowed, inhaled, or absorbed; Irritation to respiratory tract
Symptoms of Exposure: Burning sensation to mucous membranes, nausea, vomiting, headache, dizziness, respiratory distress, possible convulsions
Label Elements: Skull and crossbones, corrosion symbol

Composition / Information on Ingredients

Chemical Name: Phenethylamine
Concentration: 98-100%
CAS Number: 64-04-0
Impurities: May include trace amines or solvents from production

First Aid Measures

Inhalation: Move person to fresh air, support breathing, get medical attention
Skin Contact: Flush with copious water, remove contaminated clothing, wash with soap, seek immediate medical help for burns
Eye Contact: Rinse eyes with water for at least 15 minutes, hold eyelids open, get medical assistance
Ingestion: Rinse mouth, never induce vomiting, give water if fully conscious, get immediate medical attention
Note to Physician: Treat symptomatically and watch for severe neurological effects or respiratory compromise

Fire-Fighting Measures

Suitable Extinguishing Media: Carbon dioxide, alcohol-resistant foam, dry chemical
Unsuitable Media: Direct streams of water can spread burning liquid
Specific Hazards: Combustion releases nitrogen oxides, carbon monoxide, toxic vapors
Protective Equipment: Self-contained breathing apparatus, full protective clothing
Special Firefighting Procedures: Isolate area, use water spray to cool surfaces, prevent runoff into storm drains, keep away from inhalation of smoke or fumes

Accidental Release Measures

Personal Precautions: Evacuate unnecessary personnel, use face protection, wear gloves and apron
Environmental Precautions: Contain spill, prevent runoff to waterways or drains
Cleanup Methods: Absorb with inert material like sand, shovel into suitable chemical waste container, ventilate area well, dispose in accordance with local regulations
Decontamination: Wash spill site with soap solution, ventilate area, remove contaminated clothing safely

Handling and Storage

Handling: Avoid breathing dust, fumes, or vapor; handle in a chemical fume hood; wear goggles, gloves, lab coat
Storage Conditions: Store away from heat, light, and incompatible substances; keep container tightly closed in a well-ventilated place
Incompatibles: Strong acids, oxidizers, strong bases, halogenated compounds can cause reactions; keep away from ignition sources
Hygiene Practices: No eating, drinking, or smoking in work area, wash hands after handling

Exposure Controls and Personal Protection

Exposure Limits: No established OSHA or ACGIH limits, minimize exposure to the lowest feasible
Engineering Controls: Use chemical fume hood, mechanical ventilation
Personal Protective Equipment: Impermeable gloves (nitrile, butyl rubber), chemical splash goggles, laboratory coats, face shield for large quantities, closed footwear
Respiratory Protection: NIOSH-approved respirator in absence of adequate ventilation or during large spills
Other Protection: Safety shower and eyewash station should be accessible

Physical and Chemical Properties

Appearance: Colorless to pale yellow, oily liquid
Odor: Fishy or ammoniacal
pH: Alkaline (aqueous solution), dependent on concentration
Melting Point: -60°C
Boiling Point: 195°C
Flash Point: 85°C (closed cup)
Autoignition Temperature: 430°C
Explosion Limits: Not defined
Vapor Pressure: 0.5 mmHg at 20°C
Solubility: Miscible with water, ethanol, and organic solvents
Density: 0.96 g/cm³ at 20°C
Partition Coefficient (log Kow): Approx 1.41
Viscosity: Not significant under normal conditions

Stability and Reactivity

Chemical Stability: Stable under normal temperature and pressure
Conditions to Avoid: Exposure to air, elevated temperatures, moisture, direct sunlight
Materials to Avoid: Oxidizers, acids, acid chlorides, acid anhydrides
Hazardous Decomposition: Can release toxic fumes of nitrogen oxides, carbon monoxide, volatile organic compounds
Polymerization: Does not occur

Toxicological Information

Routes of Exposure: Inhalation, skin, eyes, ingestion
Acute Toxicity: LD50 (oral, rat): 368 mg/kg; LD50 (dermal, rabbit): Data limited
Symptoms: Severe burns, headache, agitation, severe respiratory and digestive tract irritation
Chronic Effects: Prolonged exposure can affect nervous system and cardiovascular function
Sensitization: Not fully studied
Carcinogenicity, Mutagenicity, Reproductive Toxicity: Not classed as carcinogen by IARC or NTP; limited data for mutagenic and reproductive effects

Ecological Information

Aquatic Toxicity: Harmful to aquatic organisms, low to moderate bioaccumulation potential
Persistence: Not readily biodegradable; can persist in soil or water if released
Mobility: Medium volatility, miscibility brings risk of contamination to water sources
Environmental Impacts: Spillage may disrupt aquatic habitats, toxic effect on fish and microbes
Precautions: Prevent release to environment, use containment systems for storage and handling

Disposal Considerations

Waste Treatment: Mix with suitable absorbent for incineration at approved facility
Container Disposal: Triple rinse, treat as hazardous waste, follow local and national regulations
Environmental Releases: Avoid landfill or direct drainage, special handling to prevent contamination of water or soil
Employee Training: Ensure proper training for chemical disposal, clear labeling of waste containers

Transport Information

UN Number: 2810
Proper Shipping Name: Toxic Liquid, Organic, N.O.S. (Phenethylamine)
Hazard Class: 6.1 (Toxic substances)
Packing Group: II
Label Required: Toxic
Marine Pollutant: Not listed, but take precautions for liquid cargo
Transport Precautions: Keep containers upright, avoid rough handling, document substance properly

Regulatory Information

TSCA: Listed
REACH Status: Registration required for import or manufacture in Europe
SARA 313: Not subject to reporting
California Proposition 65: Not listed as a carcinogen or reproductive toxicant
Workplace Labelling: Use compliant chemical hazard labels
Other Regulations: Check regional or national substance restrictions, chemical licensing for laboratories or manufacturing