Product Name: N-Propylamine
Chemical Formula: C3H9N
Synonyms: 1-Aminopropane, Propan-1-amine
CAS Number: 107-10-8
Recommended Use: Intermediate in organic synthesis, corrosion inhibitor, solvent
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Recommended Restrictions: Not for consumer use or food processing
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Hazard Classification: Highly flammable liquid and vapor; creates dangers of skin and eye burns; harmful if swallowed or inhaled
Hazard Statements: Causes severe skin burns and eye damage; may cause respiratory irritation; toxic to aquatic life
Signal Word: Danger
Pictograms: Flame, Corrosion, Exclamation mark
Precautionary Statements: Avoid breathing vapors; use only outdoors or in well-ventilated area; wear protective gloves, clothing, and eye protection; keep away from heat, sparks, and open flames
Physical Hazards: Vapors can travel and ignite remotely; pressure buildup possible under high temperatures
Health Hazards: Prolonged exposure leads to burns, headache, nausea, or coughing
Environmental Hazards: Toxic to aquatic organisms with long-term effects in aquatic environments
Chemical Name: N-Propylamine
Concentration: 99–100%
CAS Number: 107-10-8
Impurities: Water (<0.1%), may carry trace amounts of other low molecular amines
Other Identifiers: EC Number 203-462-3, UN Number 1277
Eye Contact: Rinse immediately with plenty of water for at least 15 minutes, keeping eyelids open; remove contact lenses only after thorough initial rinsing
Skin Contact: Remove contaminated clothing; wash skin immediately with soap and water; do not use solvents
Inhalation: Move person to fresh air; support breathing if necessary; seek medical help for persistent cough or breathing problems
Ingestion: Do not induce vomiting; rinse mouth and drink small amounts of water; seek prompt medical attention
Most Important Symptoms: Redness, pain, skin or eye burns, shortness of breath, nausea
Immediate Medical Attention: Critical in cases of severe exposure; treat for chemical burns and respiratory distress
Suitable Extinguishing Media: Use alcohol-resistant foam, dry chemical powder, or carbon dioxide; water spray for cooling
Unsuitable Media: Direct water jets may spread fire
Fire Hazards: Releases toxic ammonia and nitrogen oxides when burning
Protective Actions: Isolate area; avoid entering confined spaces without protection
Special Protective Equipment: Firefighters should wear self-contained breathing apparatus and full body protection
Explosion Hazard: Vapors heavier than air; may cause flashback ignition to source
Hazardous Combustion Products: Nitrogen oxides, carbon monoxide, ammonia
Personal Precautions: Evacuate area; ventilate space; keep away unprotected persons
Emergency Procedures: Eliminate all ignition sources; keep containers cool with water spray
Environmental Precautions: Prevent product from entering waterways, drains, or sewers
Containment: Stop leak if safe; absorb with sand, earth, or inert materials
Cleanup Methods: Pick up with non-sparking tools; place residues in sealable containers; ventilate area after cleanup
Decontamination: Wash spill site with lots of water after material removal
Handling: Avoid contact with eyes, skin, clothing; use only in fume hood or well-ventilated space; ground containers during transfer
Storage: Store in tightly sealed containers in a cool, dry, well-ventilated area; keep away from sources of ignition, oxidizers, acids
Storage Temperature: Keep below 30°C for long-term stability
Incompatible Materials: Avoid strong acids, oxidizing agents, aldehydes, halogens
Other Precautions: Keep container tightly closed; label storage containers clearly
Safe Transfer Practices: Use spark-proof tools and explosion-proof pumps
Occupational Exposure Limits: OSHA PEL: 5 ppm (13 mg/m³) TWA; ACGIH TLV: 2 ppm (as time-weighted average)
Engineering Controls: Use local exhaust ventilation; closed system transfers
Eye Protection: Chemical splash goggles and face shield
Skin Protection: Chemical-resistant gloves (nitrile, neoprene), long-sleeved clothing
Respiratory Protection: Suitable respirator if ventilation inadequate; use full-face mask for higher concentrations
Hygiene Measures: Wash hands thoroughly after handling; remove soiled clothing promptly
Environmental controls: Use secondary containment for large containers, avoid airborne concentrations
Appearance: Clear, colorless liquid
Odor: Strong, fishy, ammonia-like
Odor Threshold: Distinct and pungent at low concentrations, detectable below 1 ppm
pH: Alkaline (11–12 for 10% aqueous solution)
Melting Point: −83°C
Boiling Point: 48°C
Flash Point: −6°C (closed cup)
Evaporation Rate: Rapid under ambient conditions
Flammability: Highly flammable
Explosive Limits: 2.1%–10.4% (v/v in air)
Vapor Pressure: 222 mmHg at 20°C
Vapor Density: 2 (air = 1)
Density: 0.722 g/cm³ at 20°C
Solubility: Completely miscible in water, ethanol, ether
Partition Coefficient: log Kow = −0.36
Auto-ignition Temperature: 308°C
Decomposition Temperature: Above 200°C
Viscosity: Low, flows easily
Chemical Stability: Stable under ordinary conditions; decomposes at elevated temperatures or with loss of inhibitor
Reactivity: Reacts vigorously with acids, oxidizers, halogens; can attack copper, zinc, and alloys
Hazardous Reactions: Violent polymerization possible with strong acids or bases
Conditions to Avoid: Heat, flames, sparks, exposure to air for extended time
Incompatible Materials: Strong acids, oxidizing agents, copper, brass, silver salts
Decomposition Products: Releases ammonia, nitrogen oxides
Acute Toxicity: Oral LD50 (rat): 820 mg/kg; Dermal LD50 (rabbit): 500 mg/kg
Skin Corrosion/Irritation: Rapid, strong corrosive action with burns
Serious Eye Damage: Marked conjunctivitis, tissue injury with brief exposure
Respiratory Effects: Irritant to mucous membranes and lungs, risks asthma-like symptoms
Sensitization: Not classified as a sensitizer
Chronic Exposure: Prolonged contact leads to dermatitis, lung irritation
Mutagenicity/Carcinogenicity: Not listed as carcinogen by IARC, NTP, OSHA
Other Information: Headache, dizziness, and convulsions possible at high doses
Ecotoxicity: Toxic to aquatic life; LC50 (fish) 55 mg/L (96h), EC50 (daphnia magna) 45 mg/L (48h)
Persistence: Rapid biodegradation in soil with moderate volatility
Bioaccumulation Potential: Low, log Kow under 1 suggests negligible accumulation
Mobility in Soil: High mobility; risk for leaching into waterways
Other Adverse Effects: Raises pH of water, harmful to aquatic plants and invertebrates
Degradation Products: Ammonia, nitrites, nitrates in soil and water
Preventative Measures: Keep spills out of local water supply and storm drains
Waste Treatment Methods: Incinerate under controlled conditions; treat in chemical waste facility; neutralize with dilute acid under supervision
Container Disposal: Rinse thoroughly, puncture or crush, dispose according to local regulations
Special Precautions: Avoid discharge to environment; comply with federal, state, and local disposal laws
Disposal of Spilled Material: Collect with non-combustible absorbent; package for hazardous waste disposal
UN Number: 1277
UN Proper Shipping Name: N-Propylamine
Transport Hazard Class: 3 (Flammable liquids)
Packing Group: II
Label: Flammable Liquid, Corrosive
Special Precautions: Keep away from heat, transport in upright sealed containers
Marine Pollutant: Yes
Transport by Road/Rail: ADR/RID Class 3, Code F1
Transport by Air: IATA/ICAO regulations apply, not for passenger aircraft or mail
TSCA Status: Listed under US Toxic Substances Control Act
SARA Title III: Section 302, 304, and 313 reportable component
OSHA: Regulated as hazardous
WHMIS Classification: Class B2 (Flammable liquid), D1B (Toxic), E (Corrosive)
EU Classification: GHS/CLP: Flam. Liq. 2, Acute Tox. 4, Skin Corr. 1B, Aquatic Acute 2
REACH Status: Registered, requires exposure scenario for downstream users
Other Regulatory Listings: Not a controlled drug or listed carcinogen; subject to state and international regulations as hazardous substance