Product Name: Methylamine Hydrochloride
Chemical Formula: CH5N·HCl
Synonyms: Monomethylamine hydrochloride, Methylammonium chloride
CAS Number: 593-51-1
Manufacturer/Supplier: Listed on the container or accompanying documentation
Recommended Uses: Chemical synthesis, laboratory reagent, pharmaceutical intermediate
Contact Information: Address and emergency phone number printed on supplier label and safety sheet
GHS Classification: Acute Toxicity (oral, dermal)—Category 4; Serious Eye Irritation—Category 2; Skin Irritation—Category 2
Signal Word: Warning
Hazard Statements: Harmful if swallowed, in contact with skin, or inhaled; Causes skin irritation; Causes serious eye irritation
Pictograms: Exclamation mark
Other Hazards: Forms corrosive and irritating fumes in contact with acids, can cause respiratory tract irritation
Precautionary Statements: Avoid breathing dust, wear eye/face protection, wash hands thoroughly after handling, do not eat, drink, or smoke during use
Chemical Name: Methylamine Hydrochloride
Concentration: ≥99% by weight
CAS Number: 593-51-1
Impurities: No significant impurities present over 0.1% contributing to classification
Risk Components: No subsidiary hazardous components identified in pure form
Inhalation: Move person to fresh air, keep comfortable for breathing, seek medical attention if respiratory symptoms persist
Ingestion: Rinse mouth thoroughly with water, do not induce vomiting, get medical help if feeling unwell
Skin Contact: Remove contaminated clothing, flush skin with water for at least 15 minutes, seek advice from medical professional if irritation continues
Eye Contact: Rinse gently with water for 15 minutes while keeping eyelids open, remove contact lenses after first few minutes, medical attention recommended
General Attention: Be aware of symptoms like breathing difficulty, persistent irritation, or allergic reactions—these require professional evaluation
Suitable Extinguishing Media: Water spray, dry chemical powder, carbon dioxide, foam—use what’s appropriate for surrounding fire
Unsuitable Extinguishing Media: Do not use direct water jet, high-pressure streams could spread dust
Hazardous Combustion Products: Forms toxic gases including hydrogen chloride, carbon monoxide, nitrogen oxides
Protective Equipment: Firefighters should wear self-contained breathing apparatus, chemical-resistant clothing
Specific Hazards: Thermal decomposition leads to release of corrosive fumes, closed containers may rupture from pressure buildup
Evacuation Procedures: Remove non-essential personnel, maintain safe distance
Personal Precautions: Wear gloves, eye protection, dust mask or respirator for spills involving powder, avoid raising dust
Environmental Precautions: Avoid entry into drains or watercourses, contain spill with suitable inert material
Clean-up Methods: Sweep up using methods minimizing dust, place in appropriate waste containers, ventilate area well
Disposal: Refer to disposal section, follow local regulations for hazardous chemical release
Decontamination: Wash spill site with plenty of water after removal, remove protective clothing after clean-up and wash hands
Handling: Work in a well-ventilated area, minimize dust formation, avoid contact with skin and eyes, do not eat or drink nearby, wear recommended PPE
Storage Conditions: Keep in a tightly sealed original container, store in cool, dry places away from direct sunlight and incompatible materials like strong oxidizers
Segregation: Avoid storage near acids/bases, flammable organic substances, or foodstuffs
Special Advice: Store locked up, only trained personnel should have direct access, label all storage clearly
Occupational Exposure Limits: No official exposure limit values set for methylamine hydrochloride in most regions; use general nuisance dust limits if none provided
Engineering Controls: Work under local exhaust, keep containers closed, use process enclosures where practical
Personal Protective Equipment: Safety goggles with side shields, chemical-resistant gloves (nitrile or equivalent), lab coat or apron, dust-proof respirator for airborne concentrations above recommended exposure levels
Hygiene Measures: Wash hands before breaks and after handling, remove contaminated clothing before leaving work area, never reuse contaminated PPE
Appearance: White to off-white crystalline powder
Odor: Mild ammonia-like smell
pH (1% solution): Around 5.5-6.5
Melting Point: 230-233°C (decomposes)
Boiling Point: Not applicable (decomposes before boiling)
Solubility: Highly soluble in water
Vapor Pressure: Not significant at room temperature
Density: 0.955 g/cm3 at 25°C
Partition Coefficient (log Kow): Not available
Other Details: Decomposes upon heating, producing toxic fumes
Reactivity: Stable under recommended storage and handling conditions
Chemical Stability: Stable at room temperature if kept dry and sealed
Hazardous Reactions: Reacts with strong acids/bases, strong oxidizers, strong reducing agents
Conditions to Avoid: Heat, moisture, incompatible chemicals, static discharge
Hazardous Decomposition: Ammonia, hydrogen chloride, methylamine gas
Polymerization: Not known to occur
Acute Toxicity: Oral LD50 (rat): approximately 700 mg/kg
Skin Corrosion/Irritation: Can irritate skin on contact
Serious Eye Damage/Irritation: Strong irritant to eyes
Respiratory Sensitization: May cause cough, irritation in nose and throat
Chronic Effects: Repeated exposure can damage mucous membranes, risk increases without engineering controls
Carcinogenicity: Not listed by IARC, OSHA, NTP
Other Information: No evidence of mutagenicity or specific organ toxicity from routine lab exposures documented in literature
Toxicity to Aquatic Life: Harmful to aquatic organisms in concentrated form, especially in confined systems
Persistence and Degradability: Biodegradable in environmental conditions but high concentrations could pose risk if released
Bioaccumulation: Expected low potential based on water solubility
Mobility in Soil: High mobility, dissolves easily in water and may leach
Other Adverse Effects: Elevated level discharge should be avoided to protect water quality
Waste Disposal Methods: Collect unused or contaminated material in sealed containers, label clearly as hazardous waste
Regulations: Dispose of in accordance with local, regional, and national regulations on chemical wastes
Contaminated Packaging: Triple-rinse containers, puncture after cleaning, dispose by incineration or licensed waste handler
Avoid: Release into waterways, open dumps, or municipal waste streams
UN Number: 2923 (if classified as corrosive solid, toxic, n.o.s.)
Proper Shipping Name: Methylamine hydrochloride
Transport Hazard Class: Class 8 (corrosive substances, if applicable), Class 6.1 (toxic substances)
Packing Group: III
Environmental Hazards: No marine pollutant warning
Special Precautions: Secure packaging, provide documentation, notify transporter of hazard
Emergency Response Guide: Refer to national/international shipping guidelines
Labelling: GHS-compliant, signal word “Warning,” hazard pictogram (exclamation mark), hazard statements
Major Regulations: Subject to US TSCA, EU REACH, Canadian DSL, Australian AICS—confirm with local agency listings
Occupational Safety: OSHA hazardous chemical, must keep SDS accessible at work site
Workplace Restrictions: Restricted use in certain pharmaceutical and chemical manufacturing sectors without license
Other Information: Follow all regional environmental and chemical reporting requirements (SARA, EPCRA, etc.)
