Nanjing Finechem Holding Co.,Limited
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Material Safety Data Sheet: Isoandrosterone

Identification

Product Name: Isoandrosterone
Chemical Name: 3α-hydroxy-5α-androstan-17-one
Synonyms: 5α-Androstan-3α-ol-17-one
CAS Number: 53-42-9
Recommended Use: Laboratory research, chemical reference material
Supplier Information: Supplier address, phone number, emergency contact (crucial to fill out for anyone handling chemicals in a lab, call centers keep these lines active)
Revision Date: [Add specific date of document creation/update as internal tracking matters for audits]

Hazard Identification

Classification: Not classified as hazardous under GHS criteria
Signal Word: None required
Hazard Statements: May cause skin or eye irritation for sensitive individuals
Pictograms: None assigned
Precautionary Statements: Avoid contact with skin or eyes, work in well-ventilated areas, wear PPE if risk of dust or contact exists
Routes of Exposure: Skin, eyes, inhalation, ingestion
Other Hazards: Not flammable under normal storage, but dust could be combustible in rare conditions

Composition / Information on Ingredients

Chemical: Isoandrosterone
Concentration: 100% pure (for analytical/laboratory purposes)
Impurities: Trace byproducts from synthesis, usually <0.1% (should be referenced on batch Certificate of Analysis if present)
Molecular Formula: C19H30O2
Molecular Weight: 290.44 g/mol

First Aid Measures

Inhalation: Move exposed person to fresh air, support breathing, seek medical help for unusual symptoms
Skin Contact: Wash skin with soap and water, remove contaminated clothing, consult physician if irritation continues
Eye Contact: Rinse eyes gently with plenty of water for at least 15 minutes, keep eyelids open, seek further medical attention if discomfort remains
Ingestion: Rinse mouth, drink water, never try to induce vomiting unless directed by a medical professional, get help if symptoms show
Physician Advice: Provide label or MSDS to medical responders for relevant information on the compound

Fire-Fighting Measures

Suitable Extinguishing Media: Water spray, carbon dioxide, foam, or dry chemical for local fire suppression
Special Protective Equipment: Protective suit, full-face respirator to avoid combustion products exposure
Fire Hazards: Decomposes at high temperatures to produce carbon oxides (CO, CO₂), possibly irritating fumes
Advice for Fire Fighters: Always stay upwind, wear self-contained breathing apparatus, avoid run-off contamination
Explosion Data: Dust may form explosive mixture with air under confined settings (rare, but worth proper dust control)

Accidental Release Measures

Personal Precautions: Use gloves, lab coat, goggles, avoid breathing dust
Environmental Precautions: Prevent spillage from entering sewers, surface water, or soil—collect on absorbent material for safe waste pickup
Containment and Cleaning: Sweep up or vacuum (HEPA filter if airborne risk) with care, avoid creating dust, transfer to closed container for disposal
Emergency Procedures: Ventilate area, restrict access to exposed space, alert safety team if large spills occur or if ventilation cannot be increased

Handling and Storage

Safe Handling: Operate in well-ventilated lab, minimize dust generation, wash hands before eating or leaving work area, do not eat or drink around chemical
Storage Requirements: Keep container tightly closed, store at room temperature or as batch certificate recommends, avoid direct sunlight, separate from strong oxidizers
Special Storage Needs: Stainless steel, glass, or HDPE containers with proper labeling work best to avoid product degradation
Incompatibilities: Avoid acids, strong oxidizers, or bases (rare interactions, but those make up most chemical accidents in shared lab spaces)

Exposure Controls and Personal Protection

Engineering Controls: Fume hood or local exhaust ventilation offers reliable prevention of airborne dust exposure
Personal Protective Equipment: Nitrile or latex gloves, safety glasses/goggles, laboratory coat
Respiratory Protection: Dust mask for powder handling, full respirator for spill cleanup if dust becomes airborne
Exposure Limits: No OSHA or ACGIH exposure limits for isoandrosterone, so rely on best practices for chemical hygiene
Hygiene Measures: Wash hands after handling, avoid contact with face, store work clothing away from street clothes

Physical and Chemical Properties

Appearance: White to off-white crystalline powder
Odor: Slight or none
Odor Threshold: Not determined
pH: Not applicable (not soluble in water for practical pH measurement)
Melting Point: 168-170°C
Boiling Point: Not applicable (decomposes)
Flash Point: Not available
Flammability: Product not considered flammable under normal use, dust can combust like many organics
Solubility: Insoluble in water, soluble in ethanol/chloroform/ether
Partition Coefficient (log Pow): Available in specialized references, usually high due to steroid structure
Vapor Pressure: Negligible
Relative Density: Around 1.12 g/cm³
Decomposition Temperature: Above 200°C (releases fumes)

Stability and Reactivity

Chemical Stability: Stable under proper storage
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide, possibly irritant fumes
Conditions to Avoid: Heat, strong oxidizers, open flames
Incompatible Materials: Concentrated acids, alkali, oxidizers
Polymerization: No known polymerization reaction reported

Toxicological Information

Acute Toxicity: Not acutely toxic by oral/inhalation/dermal ways in small laboratory amounts
Skin Corrosion/Irritation: Low risk, sensitive people could experience irritation after repeated contact, best not to risk it
Serious Eye Damage/Irritation: Direct exposure might cause temporary discomfort
Respiratory Sensitization: Dust could irritate airways
Carcinogenicity/Mutagenicity/Reproductive Toxicity: No data supporting carcinogenic or mutagenic risks for isoandrosterone in humans; always handle with caution due to lack of long-term data
Long-Term Effects: No studies reporting chronic toxicity, but steroids can disrupt endocrine systems at high/continuous doses
Additional Info: Practically non-toxic at standard research use levels, but regulatory gaps remain

Ecological Information

Ecotoxicity: No comprehensive studies, but structurally related steroids disrupt aquatic life and endocrine function at trace levels, watch for runoff in water systems
Persistence/Degradability: Likely to persist if released due to steroid backbone structure, limited natural breakdown
Bioaccumulative Potential: High log Pow means potential for accumulation in aquatic organisms
Mobility in Soil: Low; adheres to organic matter
Other Adverse Effects: No observed rapid degradation—dispose with care, don’t rinse down the drain

Disposal Considerations

Waste Treatment Methods: Collect waste in dedicated container, label clearly
Disposal: Approved hazardous waste incinerator preferred, follow institutional and local regulations
Contaminated Packaging: Triple rinse and dispose as hazardous chemical waste, avoid reusing for non-compatible chemicals
Do Not: Dump into domestic waste, landfill, or municipal water without treatment or approval—environmental impact is too risky

Transport Information

UN Number: Not regulated as hazardous material for ground, air, or sea
UN Shipping Name: Not assigned due to low hazard status
Hazard Class: Not applicable
Packing Group: Not applicable
Special Precautions: Ship in sealed containers with clear labels, prevent spills during transit, include proper paperwork for customs/lab authorities to avoid unnecessary delays

Regulatory Information

TSCA Listing: Listed in USA Toxic Substances Control Act Inventory
DSL/NDSL: Confirmed status required for Canada
European Regulations: Not classified as hazardous under CLP/GHS
Other: Most countries ask for secure record-keeping, some require specific reporting (especially for steroid compounds due to regulatory rules in pharmaceuticals and sports)
Labelling: Standard chemical labels always necessary, include all hazard and precaution codes per local laws