Chemical Name: Di-N-Butylamine
Synonyms: N-Butyl-1-butanamine, Dibutylamine
CAS Number: 111-92-2
Recommended Use: Used in organic synthesis, manufacture of rubber chemicals, corrosion inhibitors, pharmaceuticals
Supplier Information: Name, address, and emergency phone number of supplier or manufacturer should be listed
Physical Description: Colorless to light yellow liquid with an amine-like odor
GHS Classification: Flammable Liquid (Category 3), Acute Toxicity – Oral (Category 4), Acute Toxicity – Dermal (Category 4), Skin Corrosion/Irritation (Category 1B), Eye Damage/Irritation (Category 1)
Pictograms: Flame, Corrosion, Exclamation Mark
Signal Word: Danger
Hazard Statements: Flammable liquid and vapor; Harmful in contact with skin or if swallowed; Causes severe skin burns and eye damage; May cause respiratory irritation
Precautionary Statements: Avoid breathing vapor/mist; Wear protective gloves, clothing, and eye/face protection; Keep away from heat, sparks, open flames; Wash thoroughly after handling; Use explosion-proof equipment
Chemical Identity: Di-N-Butylamine
Concentration: 100% for neat product
CAS Registry Number: 111-92-2
Impurities or Stabilizers: None typically present in pure material
Molecular Formula: C8H19N
Molecular Weight: 129.24 g/mol
Inhalation: Move person to fresh air at once, keep at rest, seek medical attention, give oxygen if breathing is difficult
Skin Contact: Remove contaminated clothing, flush skin with running water for at least 15 minutes, call for medical help, thoroughly clean contaminated clothing before reuse
Eye Contact: Rinse immediately with plenty of water for at least 15 minutes, lifting upper and lower eyelids, remove contact lenses if possible, seek urgent medical attention
Ingestion: Do not induce vomiting, rinse mouth thoroughly with water, provide medical attention promptly, never give anything by mouth if unconscious
Suitable Extinguishing Media: Use alcohol-resistant foam, carbon dioxide, dry chemical powder, water spray for smaller fires, pay attention to fire spread
Specific Hazards: Vapors may form explosive mixtures with air, produces toxic fumes of nitrogen oxides, ammonia, and carbon monoxide during combustion, flash point approximately 46°C (115°F)
Protective Equipment for Firefighters: Wear self-contained breathing apparatus, full protective clothing to prevent contact with skin and eyes
Special Precautions: Evacuate area, use water to cool fire-exposed containers, prevent runoff from entering waterways or sewers
Personal Precautions: Evacuate unnecessary personnel, ventilate area, restrict access, avoid breathing vapors, wear chemical-resistant gloves, goggles, and respiratory protection
Environmental Precautions: Prevent entry into drains, waterways, or soil, alert environmental authorities if contamination occurs
Containment Methods: Dike spill using inert absorbent (sand, earth, vermiculite), do not use combustible absorbents
Cleanup Procedures: Absorb with inert material, transfer to labeled chemical waste containers, dispose of as hazardous waste following local regulations, wash spill area thoroughly with detergent and water
Handling: Avoid all contact with skin, eyes, clothing; use only in well-ventilated areas; ground all equipment to prevent static discharge; keep away from ignition sources; no smoking near storage or handling areas; do not breathe vapors or mists; keep containers tightly closed
Storage: Store in original container, cool, dry, well-ventilated place, segregated from oxidizers, acids, and other incompatible materials, away from direct sunlight and sources of heat, provide secondary containment for bulk storage, protect containers from physical damage
Occupational Exposure Limits: ACGIH TLV: 5 ppm (skin), OSHA PEL: Not established
Engineering Controls: Local exhaust ventilation, fume hood, safety shower and eye wash stations nearby
Personal Protective Equipment: Splash-proof safety goggles, chemically-resistant gloves (nitrile, butyl rubber), long-sleeved lab coat or apron, flame-resistant clothing for large-scale work, use air-purifying respirator with organic vapor cartridges if exposure limits risk being exceeded, do not eat, drink, or smoke during handling
Appearance: Colorless to yellow liquid
Odor: Strong amine odor
Odor Threshold: Not determined
pH: Alkaline when mixed with water
Melting Point: -58°C
Boiling Point: 158°C
Flash Point: 46°C (open cup)
Flammability: Flammable
Vapor Pressure: 4 mm Hg at 20°C
Vapor Density: 4.5 (air = 1)
Relative Density: 0.76 g/cm³
Solubility: Partially soluble in water, miscible with most organic solvents
Partition Coefficient (log Kow): 2.27
Auto-ignition Temperature: 275°C
Decomposition Temperature: Not specified
Viscosity: Not determined
Chemical Stability: Stable under recommended storage conditions, can decompose if exposed to moisture, heat, or light
Reactivity: Reacts with strong oxidizers, acids, acid chlorides, anhydrides, produces toxic gases on decomposition
Hazardous Decomposition Products: Nitrogen oxides, carbon oxides, ammonia, possibly flammable or corrosive byproducts
Conditions to Avoid: Heat, flame, sparks, incompatibles, excess moisture
Possibility of Hazardous Reactions: Risk of violent polymerization or exothermic reactions with incompatible substances
Acute Toxicity: LD50 (oral, rat): 372 mg/kg; LD50 (dermal, rabbit): 1100 mg/kg; inhalation: vapor harmful or fatal at high concentrations
Skin Corrosion/Irritation: Severe burns, blisters, ulceration with prolonged or repeated exposure
Eye Damage/Irritation: Causes permanent eye damage, redness, tearing, pain, possible blindness
Respiratory Sensitization: Coughing, difficulty in breathing, possible chemical pneumonitis
Chronic Effects: May cause dermatitis, effects on liver or kidneys reported in animal studies, data on carcinogenicity not established, not listed as carcinogenic by NTP, IARC, or OSHA
Ecotoxicity: Toxic to aquatic organisms; LC50 (96 h, Fish): 82 mg/L; EC50 (48 h, Daphnia): 34 mg/L
Persistence and Degradability: Biodegradable under aerobic conditions but may persist in aquatic environments
Bioaccumulative Potential: Low to moderate based on partition coefficient
Mobility in Soil: Moderate mobility, potential for leaching to groundwater
Other Adverse Effects: Avoid direct releases to environment, consult environmental authorities before disposal
Product Disposal: Collect and dispose at a licensed chemical waste facility, follow local, national, and international regulations
Contaminated Packaging: Empty containers can retain product residues, triple rinse, label and send to licensed recycler or incinerator
Environmental Precautions: Prevent from entering water courses, sewers, or drainage systems
Disposal Methods: Incineration is preferred for combustible waste, never discharge to environment
UN Number: UN2347
UN Proper Shipping Name: Di-N-Butylamine
Transport Hazard Class: 3 (Flammable Liquids)
Packing Group: II
Marine Pollutant: Yes
Labeling Requirements: Flammable liquid label, corrosive label
Special Precautions for User: Secure tightly, keep upright, separate from food and feedstuff, document emergency measures on MSDS
OSHA Hazard Communication: Hazardous chemical, covered by OSHA Standard 29 CFR 1910.1200
SARA Title III: Section 313 listed chemical, require reporting for certain uses
TSCA Inventory: Listed
California Prop 65: Not listed as a cancer or reproductive toxicant
International Regulations: Included in inventories for EU (REACH), Canada (DSL), Australia (AICS), Japan (ENCS)
Other Labeling Requirements: Follow workplace labeling according to GHS guidelines and regional workplace safety laws
