Product Name: Cyclohexylamine
CAS Number: 108-91-8
Synonyms: Aminocyclohexane, Hexahydroaniline
Recommended Use: Employed in water treatment, rubber chemicals, corrosion inhibitors, pharmaceuticals, and as an intermediate in organic synthesis
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Emergency Contact: [Insert emergency phone number, preferably 24-hour service]
GHS Classification: Flammable Liquid (Category 3), Acute Toxicity – Oral (Category 3), Acute Toxicity – Dermal (Category 3), Acute Toxicity – Inhalation (Category 3), Skin Corrosion/Irritation (Category 1B), Serious Eye Damage (Category 1)
Signal Word: Danger
Hazard Statements: Harmful if swallowed, toxic in contact with skin, toxic if inhaled, causes severe skin burns and eye damage, flammable liquid and vapor
Pictograms: Flame, Skull and Crossbones, Corrosion
Precautionary Statements: Avoid all contact with skin and eyes. Use proper ventilation. Keep away from heat, sparks, and open flames. Wear chemical protective gloves and goggles.
Chemical Name: Cyclohexylamine
Concentration: 99%–100%
CAS Number: 108-91-8
Impurities: Minor trace amounts of benzene derivatives may show up based on source. Confirm specific impurity concerns through lot data from suppliers.
Inhalation: Remove person to fresh air immediately, keep at rest, supply oxygen if breathing is difficult, and seek medical help right away
Skin Contact: Wash with plenty of water for at least 15 minutes, remove contaminated clothing and shoes, get medical attention for burns or irritation
Eye Contact: Rinse cautiously with water for several minutes, remove contact lenses if possible, continue rinsing, get immediate medical help
Ingestion: Rinse mouth, do NOT induce vomiting, give water if person is conscious, seek emergency medical attention quickly
General Notes: Pay extra attention to symptoms like headache, nausea, dizziness, breathing issues, and burns or redness that don’t ease up after washing.
Suitable Extinguishing Media: Use alcohol-resistant foam, dry chemical, or carbon dioxide to douse fires
Unsuitable Extinguishing Media: Avoid water jet, can spread fire and splash
Special Hazards: Flammable vapors may form explosive mixtures with air, containers may explode when heated, toxic fumes of nitrogen oxides and ammonia may form
Protective Equipment for Firefighters: Wear full protective gear and self-contained breathing apparatus
Advice for Firefighters: Approach upwind, keep cool with water spray, use caution for runoff containing chemicals.
Personal Protection: Keep unnecessary people away, slip on suitable protective gear, gloves, goggles, and a respirator if levels are high
Environmental Precautions: Prevent spillage from entering drains, sewers, or waterways by using bunds or absorbents
Containment and Cleaning: Soak up small spills with inert material (sand or earth), put residue in chemical waste containers, flush area with lots of water if local rules allow
Large Spills: Use water spray to reduce vapors, keep away from ignition sources, evacuate if needed, gather professionals for cleanup.
Handling: Avoid breathing vapors, don’t let skin or eyes touch the liquid, only use in ventilated areas, keep sources of ignition away, use spark-free tools
Storage: Keep in tightly closed, properly labeled containers in a dry, cool, well-ventilated place locked away from incompatible substances like acids, oxidizing agents, and copper alloys
Other Notes: Keep away from heat and direct sunlight, check containers regularly for leaks, establish spill kits nearby in storage and handling areas
Incompatible Materials: Store away from strong acids, oxidizing agents, acid chlorides, acid anhydrides.
Occupational Exposure Limits: OSHA TWA: 10 ppm (41 mg/m³), ACGIH TWA: 10 ppm
Engineering Controls: Local exhaust or fume hood, use closed systems for transfer, regular air testing for vapor
Personal Protective Equipment: Chemical resistant gloves (like nitrile), safety goggles/faceshield, lab coat or chemical suit, approved respirator for vapor exposure
Hygiene Measures: Do not eat, drink or smoke nearby, wash hands and face after working, wash contaminated clothing before reuse.
Appearance: Colorless to pale yellow liquid
Odor: Fishy, ammonia-like, strong
Melting Point: -17°C
Boiling Point: 134°C
Flash Point: 27°C (closed cup)
Vapor Pressure: 8 mmHg at 20°C
Solubility: Miscible with water, ethanol, and ether
Density: 0.86 g/cm³ at 20°C
pH: Alkaline, forms basic solutions in water
Viscosity: Low viscosity, mobile liquid
Auto-Ignition Temperature: 293°C
Explosive Limits: Lower: 1.3% / Upper: 8.4% by volume in air.
Chemical Stability: Remains stable under ordinary use and storage conditions, heat or storage near incompatible chemicals influences reactions
Reactivity: Reacts rapidly with acids to produce heat and fumes, can corrode copper, brass, and zinc
Hazardous Decomposition Products: Burns or decomposes to nitrous oxides, ammonia, and carbon dioxide
Polymerization: Does not undergo hazardous polymerization in storage or transport conditions
Incompatible Materials: Strong oxidizing agents, acids, acid chlorides, acid anhydrides, copper-based alloys increase danger of runaway reactions.
Acute Toxicity: LD50 Oral Rat: 400 mg/kg, LD50 Dermal Rabbit: 360 mg/kg, LC50 Inhalation Rat: 7.6 mg/L (4h)
Skin: Corrosive, causes burns, rapid absorption may lead to systemic toxicity
Eyes: Causes severe irritation, clouding, possible blindness
Inhalation: Causes headache, dizziness, nausea, may lead to bronchitis or pulmonary edema
Chronic Effects: Prolonged exposure damages liver, kidneys, and nervous system function
Sensitization: Not classified as respiratory or skin sensitizer
Carcinogenicity: Not listed as carcinogen by IARC, NTP, OSHA.
Acute Aquatic Toxicity: Toxic to fish (LC50 for Leuciscus idus: 58 mg/L, 48 h), harmful to aquatic invertebrates
Chronic Effects: Potential bioaccumulation low but persistence in water increases ammonia release, disrupts aquatic pH balance
Persistence and Degradability: Moderate, partial breakdown by microbes in soil or water
Mobility in Soil: High, can leach through soil into waterways
Other Impacts: Spills destroy microorganisms in sewage treatment, strict controls needed to prevent pollution.
Waste Disposal: Collect liquid in labeled, sealed containers, send to licensed hazardous waste site, don’t pour down drain or onto soil
Contaminated Packaging: Rinse or triple-wash containers and treat washes as hazardous, consult local waste authority
Incineration: Send material to chemical incinerator with afterburner and scrubber for complete destruction.
UN Number: 2357
Proper Shipping Name: Cyclohexylamine
Transport Hazard Class: 8 (Corrosive), 3 (Flammable Liquid)
Packing Group: II
Labels Required: Corrosive, Flammable Liquid
Special Precautions: Secure tightly, avoid rough handling or leaks, keep transport route clear of heat, fire, and open flames, drivers need hazmat training.
OSHA: Listed as hazardous, strict workplace limits and labeling required
EPA: Toxic Substances Control Act (TSCA) inventory, specific reporting rules for environmental releases
EU Regulation: Classified as hazardous under CLP, REACH compliance demanded for import, export
SARA Title III: No threshold planning quantity, notify authorities if spill exceeds reportable quantity
Other Rules: Subject to workplace safety training, chemical hygiene, personal protective equipment use, and environmental release controls.
