Nanjing Finechem Holding Co.,Limited
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Material Safety Data Sheet: Androstenolone

Identification

Product Name: Androstenolone
Other Names: Dehydroepiandrosterone, DHEA
Chemical Formula: C19H28O2
Molecular Weight: 288.4 g/mol
Synonyms: Prasterone, 3β-hydroxyandrost-5-en-17-one
Recommended Use: Laboratory chemical, pharmaceutical research
Supplier: Contact regional supplier or manufacturer
CAS Number: 53-43-0
Emergency Contact: Refer to local emergency number and poison center

Hazard Identification

Classification: Not classified as hazardous under standard GHS guidelines
Potential Health Hazards: Alteration in endocrine functions, hormone disruption, skin and eye irritation on contact, possible aggravation of pre-existing hormone-sensitive conditions
Route of Exposure: Inhalation, ingestion, skin and eye contact
Signal Word: Caution
Hazard Statement: May cause changes in hormone levels after chronic exposure, possible reproductive system interference, potential risk of acne or gynecomastia with misuse
Pictograms: No standard hazard pictogram required unless intended for injection or oral use in unregulated contexts
Precautionary Statement: Avoid unnecessary contact and inhalation; prevent exposure by using barrier protection

Composition / Information on Ingredients

Chemical Name: Androstenolone
Purity: ≥ 98%
Impurities: Androstenedione, pregnenolone, detectable in trace amounts from synthesis
Form: Solid (powder or crystalline)
Additives: No stabilizers or preservatives present in pure chemical

First Aid Measures

Inhalation: Move to fresh air, breathe deeply, seek medical attention if hormonal side effects or respiratory distress occur
Skin Contact: Remove contaminated clothing, wash area with soap and water, monitor for symptoms like redness or rash
Eye Contact: Rinse cautiously with water for several minutes, remove contact lenses if present and easy to do, seek medical guidance if irritation persists
Ingestion: Rinse mouth, never induce vomiting unless instructed by poison control, seek medical help if drowsiness or adverse symptoms develop
Symptoms to Watch: Nausea, dizziness, headache, severe irritation or endocrine symptoms
Special Instructions: Bring a sample or label of substance for medical team if possible

Fire-Fighting Measures

Suitable Extinguishing Media: Use water spray, foam, dry chemical, or carbon dioxide
Specific Hazards: Powder form may be combustible if airborne in high concentrations, toxic fumes possible if burned (carbon oxides)
Protective Equipment: Firefighters should wear self-contained breathing apparatus and protective clothing
Other Fire-Related Instructions: Avoid inhaling smoke, prevent wash-off from runoff reaching drains or waterways

Accidental Release Measures

Personal Precautions: Use gloves, goggles, lab coat, mask (N95 or higher), isolate area
Environmental Precautions: Prevent spillage into drains, sewers, groundwater
Containment: Carefully sweep or scoop up without raising dust, place in appropriate waste container, ventilate area
Cleanup Methods: Wash spill site with water and mild detergent after removal of bulk material
Disposal of Contaminated Material: Place in sealed, labeled container for hazardous waste collection

Handling and Storage

Handling: Avoid inhalation and contact with skin or eyes, use only in well-ventilated or fume-hood conditions, minimize dust generation
Storage Conditions: Store in tightly closed original container, away from light, moisture, oxidizing agents, and incompatible materials
Temperature Requirements: Recommended storage at 2-8°C (refrigerated)
Other Storage Recommendations: Keep locked up and away from unauthorized or untrained personnel, clearly labeled as hormone-active substance

Exposure Controls and Personal Protection

Engineering Controls: Fume hood or local exhaust ventilation, laboratory safety shower and eyewash station nearby
Personal Protection: Chemical-resistant gloves (nitrile or latex), safety goggles, lab coat, dust mask or respirator if dust generation expected
Occupational Exposure Limits: No specific OSHA, NIOSH, or ACGIH limits established for Androstenolone
Hygiene Measures: Wash hands thoroughly after handling, remove contaminated clothing, do not eat or drink near product

Physical and Chemical Properties

Appearance: White to off-white crystal or powder
Odor: Odorless
pH: Not applicable in solid form
Melting Point: 148–152°C
Boiling Point: Not determined (decomposes)
Solubility: Practically insoluble in water, soluble in alcohol, acetone, ether
Vapor Pressure: Negligible at room temperature
Density: Approximately 1.1 g/cm³
Partition Coefficient (Octanol/Water): Estimated logP 2.7–3.5
Other Properties: Stable under recommended storage conditions, non-volatile

Stability and Reactivity

Chemical Stability: Stable under standard lab conditions
Thermal Decomposition: May break down at temperatures above 180°C, risk of emitting carbon oxides
Incompatible Materials: Strong oxidizing agents, direct sunlight, acids
Hazardous Reactions: No hazardous polymerization expected
Conditions to Avoid: High temperatures, high humidity, open flame, incompatible chemical agents

Toxicological Information

Acute Toxicity: Data limited, low acute toxicity reported in animals, not intended for human ingestion or injection
Routes of Exposure: Skin, eye, inhalation, ingestion
Potential Health Effects: Hormonal changes, acne, hair loss, mood swings, reproductive system impacts
Long-Term Exposure: Risk of altering hormone-dependent growth, possible link to endocrine disorders with misuse
LD50 (Rat): Not established
Other Toxicological Data: No evidence for genotoxicity or carcinogenicity under standard laboratory use

Ecological Information

Eco-Toxicity: Low toxicity to aquatic life expected in laboratory quantities
Persistence: Hormonal compounds may persist and bioaccumulate in the environment
Mobility: Low water solubility, strong soil adsorption
Biodegradability: Limited data; likely slow degradation in environment
Recommendations: Prevent release into soil, waterways, or sewer systems
Other Environmental Information: Small amounts should be collected and disposed as hazardous laboratory waste; large releases may disrupt aquatic organisms' endocrine systems

Disposal Considerations

Waste Treatment Methods: Collect material in labeled, tightly sealed disposal container for incineration or hazardous waste facility
Do Not Dispose: Do not pour into drains, surface water, or normal trash
Decontamination: Wash equipment and area with soap and water, follow-up with standard lab cleaning protocols
Waste Codes: Follow local, regional, and national regulations for hormonal pharmaceutical waste; usually not household waste

Transport Information

UN Number: Not regulated as a dangerous good
Transport Hazard Class: Not assigned
Packing Group: Not applicable
Special Precautions: Prevent exposure during shipment, seal containers thoroughly, label as hormone or laboratory reagent
DOT/IATA/IMDG: No specific restrictions for Androstenolone in most regions, shipment within original packaging

Regulatory Information

OSHA Status: Not specifically listed, general laboratory safety applies
TSCA Status: Listed (US)
EU/REACH: Not specifically listed as hazardous; must track for manufacturing/import under EU chemical rules
State and Local Regulations: Prescription and supplement restrictions apply in several regions; always check jurisdiction before procurement or disposal
SARA Title III: Not listed
Other Regulations: Workplace labeling and recordkeeping for hormone-active chemicals strongly recommended; training required for laboratory staff