Nanjing Finechem Holding Co.,Limited
Knowledge


Material Safety Data Sheet: Androst-2-En-17-One

Identification

Product Name: Androst-2-En-17-One
Chemical Formula: C19H26O
CAS Number: 963-72-6
Synonyms: 2-Androsten-17-one
Recommended Use: Research, synthesis, reference standard
Supplier: Details listed on container or invoice
Emergency Phone Number: Refer to local poison control or supplier emergency hotline

Hazard Identification

GHS Classification: Skin irritant, Sensitizer, Acute toxicity (oral, inhalation), Reproductive toxicity
Signal Word: Warning
Hazard Statements: Causes skin irritation, harmful if swallowed or inhaled, may cause allergic skin reaction, possible risk of impaired fertility
Pictograms: Exclamation mark, Health hazard
Precautionary Statements: Avoid breathing dust/fume/mist, avoid contact with skin or eyes, use personal protection, wash skin thoroughly after handling, store locked up

Composition / Information on Ingredients

Chemical Name: Androst-2-En-17-One
Concentration: >98% (unless otherwise stated)
Impurities: Trace related steroids, solvents, stabilizers depending on batch
Additives: None expected
Formula: C19H26O

First Aid Measures

Inhalation: Remove person to fresh air, monitor for breathing difficulty, seek medical attention for continued symptoms
Skin Contact: Wash with soap and water, remove contaminated clothing, use emollient if dryness occurs
Eye Contact: Rinse with water for several minutes, remove contact lenses if present, consult healthcare if irritation persists
Ingestion: Rinse mouth with water, offer water to drink, do not induce vomiting, seek medical help promptly
Notes to Physician: Treat based on symptoms, provide supportive care, consult poison information center if in doubt about treatment

Fire-Fighting Measures

Suitable Extinguishing Media: Carbon dioxide, dry powder, foam, sand
Unsafe Extinguishing Media: Direct water jet can spread powder and contaminants
Specific Hazards: Combustion can generate hazardous carbon oxides, dense smoke, possible toxic decomposition products
Protective Equipment: Firefighters need self-contained breathing apparatus, chemical-resistant gear
Additional Information: Cool containers exposed to fire with water mist, avoid runoff to drains or water sources

Accidental Release Measures

Personal precautions: Evacuate unprotected personnel, provide adequate ventilation, use personal protective equipment, avoid dust formation, remove ignition sources
Environmental precautions: Do not allow to enter sewers, drains, surface water; inform relevant authorities if material enters environment
Cleanup methods: Sweep up carefully, use damp cloth or vacuum with HEPA filter, transfer to clearly labeled, sealable container for disposal, wash area with detergent and water

Handling and Storage

Safe Handling: Wear gloves, goggles, and lab coat, work in well-ventilated space, avoid dust and direct contact, do not eat or drink in work area
Storage Conditions: Store in tightly closed original container, in a cool, dry, well-ventilated area away from moisture, heat, and sunlight
Incompatible Materials: Strong acids, oxidizing agents, bases, reducing agents
Special Requirements: Keep out of reach of children, label shelves and storage areas clearly, minimize access only to trained staff

Exposure Controls and Personal Protection

Engineering Controls: Laboratory fume hood or local exhaust, closed handling systems, eyewash station, safety shower
Respiratory Protection: Use dust mask or respirator if risk of airborne exposure exists
Hand Protection: Chemical-resistant gloves like nitrile or neoprene
Eye Protection: Chemical splash goggles or face shield
Skin and Body Protection: Laboratory coat or chemical-resistant apron, long pants, closed-toe shoes
Hygiene: Wash hands after handling, refrain from eating, drinking, or smoking in work area

Physical and Chemical Properties

Appearance: Off-white to pale yellow crystalline powder
Odor: Slight, faint or no detectable odor
pH: Not applicable (insoluble in water)
Boiling Point: Data not available, decomposes before boiling
Melting Point: 140–144°C (approximate range)
Flash Point: Data not available; thought to be >150°C
Solubility: Practically insoluble in water; soluble in ethanol, acetone, chloroform, DMSO
Vapor Pressure: Negligible at room temperature
Relative Density: 1.09–1.16 g/cm³
Partition Coefficient (log Pow): >3 (expected lipophilic behavior)

Stability and Reactivity

Chemical Stability: Stable under recommended conditions
Conditions to Avoid: Moisture, excessive heat, direct sunlight, contact with incompatible substances
Incompatible Materials: Strong acids, alkalis, oxidizers, reducers
Decomposition Products: Carbon monoxide, carbon dioxide, unidentified organic compounds may form after significant heating
Polymerization: No hazardous polymerization expected

Toxicological Information

Acute Toxicity: Data limited; estimated LD50 oral (rat): >2000 mg/kg
Skin Irritation: May cause redness, dryness, or cracking with repeated exposure
Eye Irritation: May cause stinging, redness, watering
Respiratory Effects: Inhalation might cause coughing, sore throat, or headache
Sensitization: Potential for allergic skin reaction
Chronic Effects: Endocrine activity means repeated exposure could impact reproductive hormones or fertility
Mutagenicity / Carcinogenicity: No animal carcinogenicity reported; mutagenicity unassessed
Other Information: Not intended for human consumption. Use only in controlled laboratory environments

Ecological Information

Ecotoxicity: Not tested directly, likely toxic to aquatic life due to steroid physiology effects
Biodegradability: Expected to persist in environment, not readily biodegradable
Bioaccumulation: Potential for bioaccumulation in wildlife because of lipophilicity
Mobility: Insoluble in water, expected low mobility in soil
Aquatic Toxicity: Estimated EC50 (daphnia, fish): low concentrations may disrupt hormonal balance or reproduction

Disposal Considerations

Disposal Methods: Collect material in sealed, labeled containers suitable for hazardous waste
Legal Notes: Dispose according to local, regional, and national legislation; do not pour down drain
Contaminated Packaging: Rinse containers, dispose according to chemical waste protocols
Environmental Precautions: Avoid release into water sources, municipal sewers, or natural environment by any route

Transport Information

UN Number: Not assigned for this compound
Transport Hazard Class: Not regulated under most international transport conventions
Packing Group: Not established
ADR/RID, IMDG, IATA: Not considered hazardous for ground, air, or sea transport in small laboratory quantities
Transport Conditions: Ship in sturdy, leak-proof containers, with clear labeling and documentation
Emergency Response: Notify shipper and follow safety protocol in event of spillage or damage

Regulatory Information

Inventory Listings: Not listed in TSCA, EINECS, DSL inventories (research use status only)
National Regulations: Subject to national and regional controlled substance laws depending on country
Labeling: Warning labels for toxic, irritant, and potential reproductive effects
Workplace Controls: Compliance with OSHA, NIOSH recommendations for hazardous chemicals
Restrictions: Sold for laboratory, research, not for food, drug, or cosmetic use
Additional Requirements: Employee training, written safety plan, access restriction to authorized staff only