Nanjing Finechem Holding Co.,Limited
Knowledge


5-Androstanedione: Material Safety Data Sheet (MSDS)

Identification

Product Name: 5-Androstanedione
Chemical Formula: C19H28O2
CAS Number: 846-46-8
Synonyms: Androstan-3,17-dione
Recommended Use: Laboratory reagent, research chemical
Supplier Details: Listed on original packaging
Contact for Emergency: Refer to supplier documentation or Safety Officer on site

Hazard Identification

GHS Classification: May cause reproductive toxicity, possible endocrine disruptor
Signal Word: Warning
Hazard Statements: Harmful if swallowed or inhaled; possible skin and eye irritant; may cause disruption of hormonal systems
Pictogram: Health hazard symbol
Precautionary Statements: Avoid dust formation, use personal protection, provide good ventilation

Composition / Information on Ingredients

Chemical Identity: 5-Androstanedione
Concentration: >98% (purity may vary by supplier)
Impurities: Less than 2%, includes minor steroidal byproducts
Hazardous Ingredients: None present at concentrations above disclosure limits aside from the main compound

First Aid Measures

Eye Contact: Flush with water for 15 minutes, remove contact lenses, seek medical attention
Skin Contact: Wash with soap and water, remove contaminated clothing, get medical help if irritation develops
Inhalation: Move to fresh air, keep airways open, seek medical aid for persistent symptoms
Ingestion: Rinse mouth, do not induce vomiting, call poison control or seek medical attention

Fire-Fighting Measures

Extinguishing Media: Use water spray, CO2, dry chemical, or foam, avoid direct water stream
Fire Hazards: Emits toxic and irritating fumes under combustion (CO, CO2, oxides of carbon)
Protective Equipment: Firefighters should use self-contained breathing apparatus and full protective gear
Special Information: Move containers from fire area if safe, avoid run-off into drains

Accidental Release Measures

Personal Precautions: Wear gloves, lab coat, goggles, use an approved mask for dust
Environmental Precautions: Avoid entry into drains, waterways, soil
Method for Clean Up: Sweep up using non-sparking tools, transfer to suitable closed container, ventilate area, clean residue with wet wipes or HEPA vacuum

Handling and Storage

Safe Handling: Limit skin and eye contact, use with local exhaust ventilation, minimize dust generation, do not eat, drink, or smoke in handling area
Storage: Store in tightly sealed container in a cool, dry, and well-ventilated place, protect from light, keep away from incompatible substances (strong oxidizers, acids)

Exposure Controls and Personal Protection

Engineering Controls: Use fume hood or local exhaust, maintain negative pressure where dust is produced
Personal Protection: Chemical-resistant gloves, safety goggles, lab coat, approved respirator for dust or inadequate ventilation
Hygiene Measures: Wash hands after use, do not touch face or exposed skin, change contaminated clothing

Physical and Chemical Properties

Appearance: White to off-white crystalline powder
Odor: Odorless or faint
Melting Point: 165–170°C
Boiling Point: Not determined
Solubility: Practically insoluble in water, soluble in organic solvents (ethanol, DMSO)
Vapor Pressure: Negligible at room temperature
Density: Approx. 1.12 g/cm3
pH: Not applicable

Stability and Reactivity

Chemical Stability: Remains stable under recommended handling and storage
Conditions to Avoid: High humidity, excessive heat, direct sunlight
Incompatible Materials: Strong acids, oxidizers, bases
Hazardous Decomposition Products: Carbon oxides under fire conditions

Toxicological Information

Acute Toxicity: May cause mild irritation to eyes, skin, respiratory tract; limited data available for lethal dose
Chronic Effects: Possible endocrine disruption, reproductive toxicity noted in animal studies
Routes of Exposure: Inhalation, ingestion, skin, eye
Symptoms: Local irritation, hormone-related effects with repeated or high exposure

Ecological Information

Eco-toxicity: May cause harm to aquatic life based on structure and category
Persistence & Degradability: Likely to be persistent in environment, slow to biodegrade
Bio-accumulative Potential: Medium to high, may accumulate in aquatic organisms
Mobility in Soil: Low, adsorbs to soil particles, spills may pose long-term hazard

Disposal Considerations

Waste Treatment: Incinerate or dispose via licensed hazardous waste contractor
Container Handling: Triple rinse or clean before disposal, follow hazardous waste protocols
Regulatory Disposal Class: Treat as hazardous chemical waste, refer to local and national regulations

Transport Information

UN Number: Not regulated under most transport regulations
Proper Shipping Name: Not assigned
Hazard Class: Not classified
Packing Group: Not assigned
Special Precautions: Double containment recommended, keep separate from food and feed

Regulatory Information

TSCA: Listed or exempt
REACH: Not registered, for research use
SARA Title III: Not listed
California Prop 65: Not specifically listed, may require notification based on use
WHMIS Classification: D2A (Toxic Material Causing Other Toxic Effects)
Other Restrictions: Sale and use restricted to qualified personnel, not for clinical or veterinary applications, consult local laws for more details