Product Name: 5-Androstanediol
Chemical Name: 5α-Androstane-3β,17β-diol
Synonyms: Androstane-3,17-diol, 3β,17β-Dihydroxy-5α-androstane
CAS Number: 571-20-0
Recommended Use: Laboratory research, reference material
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Classification: Not listed as hazardous under GHS
Physical Hazards: Potential combustible dust
Health Hazards: May irritate eyes, skin, respiratory tract; may disrupt endocrine system; possible target organ effects
Warning Symbols: None mandated, but avoid dust clouds
Known Risks: No acute toxicity data published; long-term effects uncertain
Precautionary Statements: Minimize inhalation, avoid prolonged contact with skin, keep away from food, drink, and animal feed
Chemical Identity: 5-Androstanediol
Purity: >98% (typical for lab use)
Impurities: Residual solvents, unknown minor steroids
Molecular Formula: C19H32O2
Molecular Weight: 292.46 g/mol
Relevant Components: None other than active ingredient
Inhalation: Remove exposed person to fresh air, monitor for breathing difficulty, call doctor if symptoms persist
Skin Contact: Remove contaminated clothing, wash with mild soap and water, seek care if rash or irritation develops
Eye Contact: Rinse cautiously with water for several minutes, take out lenses if present and easy, get medical advice with persistent redness
Ingestion: Rinse mouth thoroughly, seek immediate medical attention, avoid forced vomiting unless instructed by poison control
Note for Physicians: No specialized antidote, supportive treatment recommended
Suitable Extinguishing Media: Dry chemical, CO2, foam, water spray
Unsuitable Extinguishing Media: Straight streams of water (dust dispersal hazard)
Specific Hazards: May release smoke, carbon monoxide, carbon dioxide under combustion
Protective Gear: Self-contained breathing apparatus, full protective gear for firefighters
Special Procedures: Cool exposed containers, prevent run-off into waterways, remain upwind
Personal Precautions: Use appropriate personal protective equipment, restrict unprotected individuals access
Environmental Precautions: Prevent release into drains, ditches, and soil
Clean-Up Methods: Sweep up powder carefully, avoid airborne dust, collect into labeled containers, wash area with plenty of water
Spill Response: Local authorities may require reporting; consult safety advisor
Handling: Work in well-ventilated area, avoid breathing dust, avoid skin and eye contact, use minimum quantities
Storage: Store in cool, dry, locked cabinet, keep container tightly closed, segregate from strong oxidizers and acids
Storage Temperature: Below 25°C
Incompatible Materials: Strong acids, strong bases, oxidizers
Hygiene Measures: Wash hands after handling, don’t eat or drink near material
Occupational Exposure Limits: No national exposure limit established
Engineering Controls: Local exhaust ventilation, closed system preferred
Personal Protective Equipment: Nitrile gloves, lab coat, safety glasses with side shields, NIOSH-approved dust mask if airborne concentrations risked
Environmental Controls: Avoid exhaust to external atmosphere; use filters if material handled in bulk
Appearance: White to off-white crystalline powder
Odor: Odorless
pH: Not applicable (insoluble in water)
Melting Point: 190°C – 194°C
Boiling Point: Decomposes before boiling
Solubility in Water: Insoluble
Solubility (Other): Soluble in ethanol, DMSO, slightly in methanol
Vapor Pressure: Negligible
Density: Approx. 1.11 g/cm³
Partition Coefficient: Log P estimated >2 (lipophilic)
Flash Point: Not determined
Chemical Stability: Stable under standard conditions
Conditions to Avoid: Heat, light, moisture, contact with incompatible materials
Hazardous Reactions: No polymerization expected
Decomposition Products: CO, CO2, possible hydrocarbon fragments
Incompatibilities: Strong oxidizers, acids, alkalis
Acute Toxicity: Animal toxicity data not established for this compound
Chronic Toxicity: Potential for endocrine disruption with prolonged exposure
Routes of Exposure: Inhalation, ingestion, skin, eye contact
Symptoms: Headache, dizziness, irritation, skin rash; hormonal effects possible with repeated exposure
Carcinogenicity: Not listed as carcinogen by NTP, IARC, OSHA
Mutagenicity: Not determined
Reproductive Effects: Concerns based on structural similarity to related steroids
Ecotoxicity: No measured data; expected low acute toxicity to aquatic life at laboratory scales, risk to ecosystem from hormone-like activity
Persistence/Degradability: Poorly biodegradable, may persist in sediment
Bioaccumulation: Potential judged moderate for aquatic organisms due to lipophilicity
Mobility in Soil: Low water solubility, likely to adsorb to soil and sediment
Other Hazards: Disruption of hormone balance in aquatic organisms likely with repeated environmental contamination
Waste Treatment: Manage as hazardous laboratory chemical waste
Container Disposal: Triple rinse, remove label, follow institutional hazardous waste procedures
Regulatory Disposal Code: Check local hazardous waste listing; likely included as pharmaceutical waste
Preferred Disposal: Incineration with flue gas scrubbing; avoid landfill dumping
Precautions: Never flush down drain, never mix with household garbage
UN Number: Not regulated for transport
Proper Shipping Name: Laboratory chemical, n.o.s.
Hazard Class: Not classified as transport hazard
Packing Group: N/A
Marine Pollutant: Not listed, but avoid marine release
Transport Precautions: Seal container, double bag, label clearly, keep upright during transport
US Regulations: Not scheduled under Controlled Substances Act, may fall under regulatory controls for research chemicals
OSHA: Not specifically regulated
TSCA Status: May not be listed
EU Regulations: Not registered under REACH, subject to evaluation for laboratory use
State/Local: Local rules on steroid handling could apply
SARA Title III: Not listed
Other Considerations: Institutional controls may apply, including staff training and restricted access for hormone/muscle-building agents
