Product Name: 4-Androstenedione
Chemical Formula: C19H26O2
CAS Number: 63-05-8
Synonyms: Androst-4-ene-3,17-dione; 17-Oxoandrost-4-ene-3
Manufacturer: Listed on packaging or supplier documentation
Contact Number: Refer to supplier
Recommended Use: Research, chemical synthesis
Restrictions on Use: Not for food, drug, or household use
Classification: Reproductive toxicity, Suspected carcinogen
GHS Label Elements: Signal word: Danger; Pictograms: Health hazard
Hazard Statements: May cause harm to unborn child, suspected of causing cancer, harmful if inhaled, causes skin and eye irritation
Precautionary Statements: Avoid breathing dust or vapor, wear protective gloves and eye protection, wash hands after handling, do not eat drink or smoke during use
Routes of Exposure: Inhalation, skin contact, eye contact, ingestion
Health Hazards: Endocrine disruption, respiratory tract irritation, possible organ effects from repeated exposure
Chemical Name: 4-Androstenedione
Concentration: 98-100%
Impurities: Minor organic impurities, not considered significant for hazard classification
Molecular Weight: 286.41 g/mol
Other Ingredients: Does not contain preservatives, stabilizers, solvents, or diluents
Eye Contact: Flush with clean water for at least fifteen minutes, hold eyelids open, remove contact lenses if present and easy
Skin Contact: Wash skin thoroughly with plenty of soap and water, remove contaminated clothing
Inhalation: Move to fresh air, keep comfortable for breathing, seek medical attention if symptoms occur
Ingestion: Rinse mouth with water, do not induce vomiting, seek immediate medical advice
Important Symptoms: Hormonal disturbances, respiratory irritation, coughing, skin redness, eye watering
Advice to Physicians: Symptomatic treatment, address hormone-related symptoms directly, monitor for acute overexposure signs
Suitable Extinguishing Media: Dry chemical, carbon dioxide, foam, water spray
Unsuitable Media: Direct water jet may spread material
Specific Hazards: Combustion products include carbon oxides, acrid smoke
Protective Equipment: Firefighters should wear self-contained breathing apparatus and full protective clothing
Special Procedures: Prevent firewater contamination, use water to cool unopened containers
Personal Precautions: Avoid dust formation, ventilate area, use personal protective equipment
Environmental Precautions: Prevent entry into drains, soil, or waterways
Cleanup Methods: Sweep up and place in well-sealed, labeled containers, clean residues with damp cloth, avoid dry sweeping
Disposal: Place collected material in container for hazardous waste collection, avoid uncontrolled release
Handling: Use in well-ventilated areas, avoid generation of dust and direct contact with skin or eyes, do not breathe dust, keep containers tightly closed
Basic Hygiene: Wash hands and face after handling, avoid eating or drinking in work area
Storage Conditions: Keep container tightly closed in a cool, dry place, store away from direct sunlight, incompatible substances such as strong oxidizers or acids
Storage Temperature: Store at 2–8°C for stability
Packaging Materials: Use original packaging or compatible chemical-resistant containers
Exposure Limits: No established occupational exposure limits for this compound
Engineering Controls: Use fume hood or local exhaust ventilation
Personal Protection: Safety goggles for eyes, chemical-resistant gloves, lab coat, particle mask or respirator for air, avoid open skin exposure
Hygiene Measures: Do not eat, drink, or smoke during handling, remove contaminated clothing and wash before reuse
Appearance: White to off-white crystalline powder
Odor: Odorless
Melting Point: 163–166°C
Boiling Point: Not applicable (decomposes)
Solubility: Practically insoluble in water, soluble in organic solvents like ethanol and acetone
Vapor Pressure: Negligible
pH: Not available
Density: 1.18 g/cm3
Partition Coefficient (log P): 2.62 (estimated)
Flash Point: Not readily flammable
Stability: Stable under recommended conditions
Chemical Stability: Stable at room temperature and under recommended storage conditions
Hazardous Reactions: Avoid strong oxidizers, strong acids
Decomposition Products: Carbon monoxide, carbon dioxide, possibly toxic fumes in fire
Conditions to Avoid: Excessive heat, open flames, moisture, and light
Polymerization: Not known to polymerize
Acute Toxicity: Data on acute toxicity in humans and animals limited
Skin Contact: May cause irritation, redness
Eye Contact: May cause irritation, watering
Inhalation: Respiratory tract irritation, coughing
Ingestion: Hormonal effects possible due to androgenic activity
Chronic Exposure: Disruption of endocrine system, possible carcinogenic effects, reproductive toxicity
Sensitization: Not classified as a sensitizer
Carcinogenicity: Possible but not well-established; long-term effects uncertain
Ecotoxicity: Limited data available, possible bioaccumulation, may pose hazard to aquatic life
Persistence and Degradability: Likely persistent in the environment due to steroid structure
Mobility in Soil: Moderately mobile in soil, insoluble in water
Bioaccumulation: Structure suggests potential for bioaccumulation along aquatic food chain
Other Effects: Endocrine disruptor, potential interference with reproductive cycles in aquatic species
Waste Disposal Methods: Dispose as hazardous chemical waste, follow local regulations
Container Disposal: Triple rinse before discarding in accordance with local guidelines
Sewage Disposal Restrictions: Do not discharge into drains or water bodies
Incineration: Use approved chemical incinerator, avoid formation of toxic exhaust
UN Number: Not regulated for transport under international law
Transport Hazard Class: Not classified
Packing Group: Not assigned
Proper Shipping Name: Chemical, N.O.S. (contains 4-Androstenedione)
Special Precautions: Secure packaging to prevent spillage or leaking, keep away from food and feedstuff during transportation
Transport Labels: No specific hazard labels required
Regulatory Status: Not listed by OSHA, IARC, or NTP as carcinogen; may be restricted under pharmaceutical or hormone-related legislation
SARA Title III: Not subject to reporting requirements
California Proposition 65: Not listed
TSCA Status: Included for research and development use; not listed for commercial food or drug use
REACH: Not registered for commercial use in the European Union
Other Regulations: Handle as controlled substance in some jurisdictions due to hormonal properties
