Product Name: 4-Androstenediol
Chemical Name: Androst-4-ene-3β,17β-diol
Synonyms: 4-AD; 4-androstene-3beta,17beta-diol
CAS Number: 1632-05-7
Molecular Formula: C19H30O2
Product Use: Intermediate in steroid research, chemical synthesis
Supplier: [Insert Manufacturer/Supplier Name]
Contact Details: [Insert Emergency Phone Number]
Classification: Not classified as hazardous under GHS
Potential Health Effects: Possible effects include hormonal disruption, skin and eye irritation, respiratory discomfort if inhaled
Warning Symbols: None assigned
Signal Words: None established
Precautionary Statements: Avoid dust clouds, contact with eyes and broken skin; avoid breathing dust
Target Organs: Endocrine system, skin, eyes
Other Hazards: Not flammable, but dust can present a mechanical hazard in large amounts
Chemical Identity: 4-Androstenediol
Content: ≥ 95% pure
Impurities: Minor derivatives of steroid backbone (<5%)
Additives: None identified
Allergenic Components: No known protein contaminants
Inhalation: Move to fresh air quickly, monitor for breathing difficulties, rinse mouth, consult a physician if symptoms develop
Skin Contact: Remove contaminated clothing, wash skin thoroughly with plenty of water and soap, seek medical help for persistent redness or irritation
Eye Contact: Flush open eyes with running water for 15 minutes, remove contact lenses if present and easy to do, seek medical attention for ongoing pain or visual changes
Ingestion: Rinse mouth thoroughly, drink water if conscious, seek urgent medical care, do not induce vomiting
Symptoms: Hormonal imbalance, short-term irritation to mucous membranes or skin
Suitable Extinguishing Media: Use water spray, dry chemical powder, carbon dioxide, or foam
Unsuitable Media: Do not use a strong water jet which may spread powder
Fire Hazards: Powder can disperse in air, but doesn't burn easily
Special Protective Equipment: Firefighters should wear self-contained breathing apparatus, standard protective gear
Decomposition Products: Smoke, CO, CO2, trace organic vapors if burning
Advice for Firefighters: Stay upwind, avoid inhaling dust or combustion fumes, keep containers cool with water spray
Personal Precautions: Wear safety goggles, gloves, dust mask; keep unnecessary personnel away
Environmental Precautions: Prevent spilled material from entering drains, surface water, or soil
Cleanup Methods: Scoop solids with non-sparking tools, avoid raising dust, clean area with damp cloth, ventilate area thoroughly
Disposal of Waste: Collect in sealable containers for proper chemical waste disposal
Other Considerations: Notify appropriate authorities in big spills, sweep carefully to prevent mechanical irritation
Handling Practices: Open containers with care, avoid dust generation, use in a ventilated workspace, keep away from open wounds or mucous membranes
Hygiene Measures: Wash hands after handling, do not eat or drink near product, keep work clothes separate
Storage Requirements: Store in tightly sealed container, keep in a cool, dry, well-ventilated location, away from direct sunlight or heat sources
Incompatible Materials: Moisture, strong oxidizers, acids
Packaging Materials: Glass or high-grade plastic containers with tamper-evident seals
Exposure Limits: No occupational exposure limits established
Engineering Controls: Use local exhaust ventilation if available; install HEPA filters for air if dust-generating
Eye Protection: Wear protective safety glasses or goggles
Skin Protection: Use chemical-resistant gloves (nitrile, latex), lab coat, long pants
Respiratory Protection: Wear a dust mask or respirator (NIOSH-approved) if dust levels go up
General Safety: Wash up after use, do not touch face or eyes until cleaned, avoid inhaling dust
Appearance: White to off-white crystalline powder
Odor: Odorless or faint sweet aroma
pH: Not applicable (solid material)
Melting Point: 178–180°C
Boiling Point: Not available (decomposes)
Flash Point: Not determined
Solubility: Insoluble in water, soluble in organic solvents like ethanol, methanol, chloroform
Density: About 1.12 g/cm³
Vapor Pressure: Negligible at room temperature
Partition Coefficient (Log P): Estimated >2 (hydrophobic character)
Chemical Stability: Stable in dry, dark conditions
Reactive Conditions: Moisture, prolonged exposure to strong light, heat
Incompatible Materials: Strong oxidizers, strong acids, alkali metals
Hazardous Decomposition: Carbon monoxide, carbon dioxide, trace organic fragments
Polymerization: Product does not polymerize
Sensitivity to Static Discharge: Low, but finely divided dust could generate static
Acute Toxicity: No acute toxicity data available; estimated low oral and dermal toxicity in small amounts
Skin Irritation: May cause local redness or itching on prolonged contact
Eye Irritation: Dust can cause mechanical irritation, redness, tearing
Inhalation Effects: Mild irritation to upper respiratory tract if dust present
Chronic Effects: Risks of hormonal imbalance, possible reproductive changes with long-term misuse or high exposures
Carcinogenicity: Not listed by IARC, OSHA, or NTP as a carcinogen
Sensitization: No evidence of allergic sensitization reported
Mutagenicity: No data suggest mutagenic hazards
Environmental Fate: Poor water solubility, binds to soil and organic matter, slow biodegradation
Aquatic Toxicity: No specific data, but steroid analogs may disrupt aquatic organisms’ hormone systems at significant concentrations
Bioaccumulation: Potential for low-level accumulation due to lipid solubility
Mobility in Soil: Limited mobility, retention in upper soil layers
Hazard to Wildlife: Residues could interfere with wildlife endocrine systems if released in bulk
Long-Term Effects: Environmental monitoring recommended when working with larger quantities
Disposal Methods: Dispose in accordance with local, state, and federal waste regulations as controlled laboratory waste
Recommended Disposal: Incinerate in licensed facility or submit to hazardous waste collection point
Container Disposal: Triple-rinse empty containers and dispose as chemical waste
Precautions: Do not allow material to enter water systems, drains, or open landfills
Special Instructions: Label waste containers clearly with chemical identity and hazard notice
UN Number: Not regulated
Proper Shipping Name: Not classified as dangerous for transport
Transport Hazard Class: Not assigned
Packing Group: None assigned
Marine Pollutant: Not regulated as marine pollutant
Bulk Transport: Avoid transport with food or feed items, prevent spillage and dust dispersal
Special Precautions: Ship in tightly sealed, original packaging; avoid temperature extremes during transit
USA TSCA: Listed
EU REACH: Not registered
Canada DSL/NDSL: Status not confirmed
OSHA HazCom: Not considered hazardous
WHMIS: Not classified as controlled
California Prop 65: Not listed
Other Regulations: Subject to controls under athletic doping agencies in many jurisdictions; handle under institutional guidelines for research chemicals
Labeling: Follow local requirements for substances with hormone action; maintain inventory records for laboratory use
