Product Name: 3-Amino-2-Nitrobenzonitrile
Synonyms: o-Nitro-m-aminobenzonitrile
Chemical Formula: C7H5N3O2
CAS Number: 3167-52-2
Recommended Use: Chemical research, intermediate for organic synthesis
Restrictions: Professional laboratory and industrial settings only
Manufacturer: [Insert Manufacturer Name], [Insert Address], [Insert Emergency Contact Number]
GHS Classification: Acute toxicity (oral, dermal, inhalation), Skin/eye irritation, Environmental hazard
Signal Word: Danger
Hazard Statements: Harmful if swallowed, toxic in contact with skin or if inhaled, causes skin and eye irritation. Dangerous to aquatic life with long-lasting effects.
Precautionary Statements: Avoid breathing dust or fumes. Wash exposed skin thoroughly after handling. Wear protective gloves, protective clothing, eye protection, and face protection. Prevent release to the environment.
Hazard Symbols: Skull and crossbones, exclamation mark, environment
Pictograms: GHS06, GHS07, GHS09
Chemical Identity: 3-Amino-2-Nitrobenzonitrile
CAS Number: 3167-52-2
EC Number: Not available
Concentration: ≥98% by weight
Impurities: Trace aromatic nitriles (<2%), not known to affect classification
Additives: None
Inhalation: Move affected person to fresh air at once. Provide oxygen or artificial respiration if breathing is difficult or stopped. Seek immediate medical care.
Skin Contact: Remove contaminated clothing immediately. Rinse skin with plenty of water using shower if available for at least fifteen minutes. Get prompt medical attention.
Eye Contact: Flush eyes thoroughly with water for several minutes, holding eyelids open. Remove contact lenses if present. Seek medical advice without delay.
Ingestion: Rinse mouth with water, do not induce vomiting unless directed by medical personnel. Give water to dilute. Immediate hospital treatment required.
Most Important Symptoms/Effects: Burning sensation, coughing, shortness of breath, possible dizziness, nausea, allergic reactions, possible delayed symptoms including organ damage.
Suitable Extinguishing Media: Foam, dry powder, carbon dioxide (CO2), water spray (do not use direct water stream)
Specific Hazards: Emits toxic fumes (nitrogen oxides, cyanides, carbon monoxide) under fire conditions
Protective Equipment: Full protective gear including self-contained breathing apparatus
Special Procedures: Remove containers from fire area if it can be done safely. Prevent fire-fighting water from entering drains or watercourses.
Combustion Products: CO, CO2, HCN, NOx
Personal Precautions: Evacuate area. Wear chemical-resistant gloves, goggles, protective clothing, and mask with particle filter.
Environmental Precautions: Prevent further leakage or spillage if safe. Avoid discharge into drains. If large spills occur, inform environmental authorities.
Cleanup Methods: Collect solid material with non-sparking tools, sweep up and place in clearly labeled, sealable containers for disposal. Ventilate area thoroughly.
Decontamination: Wash surface with soap and water. Dispose of contaminated cleaning materials as hazardous waste.
Handling: Use only in well-ventilated areas, preferably under a fume hood. Prevent eye and skin contact. Avoid inhalation of dust. Keep away from heat and open flame. Never eat, drink, or smoke during use.
Storage Conditions: Store in tightly closed, clearly labeled containers away from incompatibles such as strong oxidizers and acids, in a cool, dry, and well-ventilated area. Protect from moisture and direct sunlight. Keep out of reach of children and untrained individuals.
Storage Class: Toxic and harmful substances.
Exposure Limits: No current occupational exposure limit established for this compound.
Engineering Controls: Use local exhaust ventilation. Work in chemical fume hood.
Respiratory Protection: Wear suitable respirator with particulate and organic vapor filters if dust or vapors expected.
Hand Protection: Chemical-resistant gloves (nitrile, neoprene).
Eye Protection: Chemical splash goggles or full-face shield.
Skin/Body Protection: Laboratory coat, impervious clothing, closed footwear.
Hygiene Measures: Wash hands promptly after handling. Keep work clothing separate from other clothing. Avoid contact with skin, eyes, and clothing.
Appearance: Pale yellow to light brown crystalline powder
Odor: Slightly aromatic
Odor Threshold: Not determined
pH: Not applicable (insoluble in water)
Melting Point: 162 – 170°C
Boiling Point: Not available (decomposes)
Flash Point: >140°C (closed cup, estimate)
Evaporation Rate: Not determined
Flammability: Not classified as flammable but can burn
Explosion Limits: No data available
Vapor Pressure: Negligible at room temperature
Vapor Density: Not determined
Relative Density: 1.43 (estimated)
Solubility: Sparingly soluble in water, freely soluble in organic solvents (DMF, DMSO, acetone)
Partition Coefficient: log Kow 1.6 – 2.1 (estimated)
Auto-ignition Temperature: Not determined
Decomposition Temperature: >180°C
Molecular Weight: 163.14 g/mol
Viscosity: Not applicable (solid)
Chemical Stability: Stable under recommended storage conditions, sensitive to extreme heat and moisture
Reactivity: Reacts with strong oxidizing agents, strong acids. May decompose with release of toxic gases on prolonged heating or exposure to acids.
Hazardous Decomposition: Toxic gases including NOx, CO, CO2, HCN
Hazardous Polymerization: Not expected
Conditions to Avoid: Open flames, high temperatures, contact with incompatible chemicals
Incompatible Materials: Strong acids, strong bases, oxidizing agents
Acute Toxicity: Oral LD50 (rat): 50-200 mg/kg (estimate); Inhalation, Dermal toxicity not fully defined but presumed harmful
Skin Corrosion/Irritation: Causes irritation and possible allergic reaction in sensitive individuals
Eye Damage/Irritation: Causes serious eye irritation
Respiratory Sensitization: May cause allergic reactions and irritation upon inhalation
Symptoms: Sore throat, coughing, headache, dizziness, skin redness, eye watering
Chronic Effects: Prolonged exposure may affect liver, kidneys, and central nervous system
Carcinogenicity: Not listed by IARC, NTP, OSHA
Mutagenicity: Data insufficient
Reproductive Toxicity: Data not available
Other Effects: Possible blood effects (methemoglobinemia) at high doses
Toxicity: Toxic to aquatic life; can cause long-term adverse effects in the aquatic environment
Persistence and Degradability: Not easily biodegradable, may persist in soil and water
Bioaccumulative Potential: Possible due to moderate log Kow, but significant accumulation not expected
Mobility in Soil: Slight to moderate mobility based on solubility and partition coefficient
Other Adverse Effects: Avoid release to environment. Compound may disrupt local aquatic ecosystems.
Waste Disposal: Dispose of material as hazardous waste per local, regional, and national regulations
Container Disposal: Triple rinse empty containers with solvents and send for chemical waste incineration
Methods: Do not dispose in drains or natural water courses. Do not mix with household garbage. Contract qualified licensed disposal contractors.
Additional Notes: Chemical waste generators must comply with environmental standards. Avoid exposure during disposal activities.
UN Number: 2811
UN Proper Shipping Name: Toxic solid, organic, n.o.s. (contains 3-Amino-2-Nitrobenzonitrile)
Transport Hazard Class: 6.1 (Toxic substances)
Packing Group: III
Environmental Hazards: Marine pollutant
Special Precautions: Avoid transport with food, oxidizers, acids. Transport in well-sealed, secure containers.
Label: Toxic (skull and crossbones), Environment
TSCA (USA): Listed or exempted
REACH (EU): Pre-registered or subject to other registration procedures
Chemical Inventory Status: Consult national lists for detailed status
SARA 313/Title III: Not subject
WHMIS (Canada): D1B (Toxic material causing immediate and serious toxic effects)
OSHA: Classified as hazardous chemical
Restrictions: For industrial and laboratory use only. Not for household or consumer use.
