Product Name: 2-N-Butylamine
Synonyms: sec-Butylamine, 2-Aminobutane
CAS Number: 13952-84-6
Recommended Use: Intermediate in organic synthesis, laboratory reagent
Manufacturer/Supplier: [Insert name, address, phone]
Emergency Phone Number: [Insert emergency contact number]
GHS Classification: Flammable liquid (Category 2), Acute toxicity – inhalation (Category 3), Skin corrosion (Category 1B), Eye damage (Category 1), Acute aquatic toxicity (Category 2)
Hazard Symbols: Flame, Corrosion, Exclamation mark
Signal Word: Danger
Hazard Statements: Causes severe skin burns and eye damage, flammable liquid and vapor, toxic if inhaled, harmful to aquatic life
Precautionary Statements: Keep away from heat, avoid breathing vapors, wear protective gloves, wash thoroughly after handling, avoid release to environment
Chemical Identity: 2-N-Butylamine
Formula: C4H11N
Concentration: ≥ 98%
Impurities: Possible traces of water or other amines
EC Number: 237-732-2
Inhalation: Remove to fresh air. Seek medical help if symptoms appear such as coughing, dizziness, trouble breathing.
Skin Contact: Take off contaminated clothing and rinse skin with water for at least 20 minutes. Seek immediate medical attention.
Eye Contact: Rinse cautiously with water for at least 20 minutes, holding eyelids open. Remove contact lenses if easy to do. Get medical attention at once.
Ingestion: Do not induce vomiting. Rinse mouth with water. Seek medical help without delay. Give water if conscious unless advised otherwise by a medical professional.
Suitable Extinguishing Media: Use dry chemical, foam, carbon dioxide. Water spray may be used to cool containers.
Fire Hazards: Vapors can form explosive mixtures with air. Flashback is possible. Burns with intense, irritating smoke.
Protective Equipment: Wear self-contained breathing apparatus, chemical-resistant clothing. Stay upwind.
Special Precautions: Avoid inhaling fumes. Prevent run-off from entering drains or watercourses.
Personal Precautions: Remove ignition sources, ventilate area, avoid inhalation and skin/eye contact, use personal protective gear (Nitrile gloves, goggles, lab coat, respirator if needed).
Spill Containment: Use non-sparking tools to contain and collect spilled liquid using inert absorbent material (sand, earth).
Cleanup: Scoop up in a leak-proof container for disposal. Wash area with plenty of water.
Environmental Precautions: Prevent further leakage or entry into waterways, soil, or sewers. Notify authorities if a significant spillage occurs.
Handling: Wear correct protective clothing, avoid breathing fumes, prevent skin or eye contact. Work in a well-ventilated space. Keep containers tightly closed except during use.
Hygiene: Wash hands thoroughly before eating, drinking, or smoking. Remove contaminated clothing and wash before reuse.
Storage Conditions: Store in tightly sealed containers away from heat, open flame, oxidizers, acids. Keep in a cool, dry place with adequate ventilation. Segregate from incompatible substances.
Occupational Exposure Limits: ACGIH TLV: 5 ppm, 15 mg/m³ (as butylamines)
Engineering Controls: Use local exhaust ventilation, process enclosure, or general room ventilation.
Personal Protection: Wear chemical-resistant gloves (nitrile), splash-proof goggles, lab coat, and suitable respirator if airborne exposure is possible. Remove contaminated clothing immediately.
Environmental Exposure Controls: Prevent chemical from entering drains or watercourses.
Appearance: Clear to pale yellow liquid
Odor: Strong, ammonia-like
Odor threshold: Detectable at low concentrations
Boiling Point: 63°C–65°C
Melting Point: −115°C
Vapor Pressure: 170 mm Hg at 20°C
Flammability: Flammable
Explosive Limits: 1.8% (lower), 12% (upper)
Flash Point: −2°C (closed cup)
Solubility: Miscible with water, ethanol, ether
Specific Gravity/Density: 0.74 (water = 1)
pH: alkaline, about 11 (1% solution)
Partition Coefficient (n-octanol/water): 0.7
Chemical Stability: Stable under standard conditions. Rapidly degrades in sunlight.
Reactivity: Violent reaction with strong acids, oxidizing agents, halogens, acid anhydrides.
Hazardous Decomposition: Produces toxic gases such as nitrogen oxides, ammonia, hydrocarbons, and carbon monoxide under combustion.
Polymerization: Hazardous polymerization does not occur with this compound.
Routes of Exposure: Inhalation, Skin contact, Eye contact, Ingestion
Acute Toxicity Data: Oral LD50 (rat): 530 mg/kg; Dermal LD50 (rabbit): 350 mg/kg; Inhalation LC50 (rat): Estimated 1.7 mg/L (4 h)
Effects of Exposure: Burns skin and eyes. Vapors cause nose, throat, lung irritation. Inhalation or ingestion causes nausea, dizziness, headache, drowsiness, loss of coordination. Large doses may cause lung edema, confusion, unconsciousness.
Chronic Effects: Prolonged exposure leads to dermatitis, mucous membrane damage, liver and kidney impairment in severe cases.
Carcinogenicity: No evidence from IARC, NTP, or OSHA related to 2-N-butylamine.
Aquatic Toxicity: Harmful to aquatic organisms. LC50 (fish, 96h): ~89 mg/L. Toxic to algae and invertebrates at low concentrations.
Degradability: Rapidly biodegradable under aerobic environmental conditions.
Bioaccumulative Potential: Low (log Kow: 0.7), unlikely to persist in the food web.
Mobility in Soil: High mobility due to water solubility; may reach groundwater.
Other Adverse Effects: Alters local pH in water systems, which endangers aquatic life.
Waste Treatment Methods: Incinerate at high temperature in approved facility or treat with suitable chemicals for neutralization under controlled conditions.
Container Disposal: Remove residue from container, triple rinse, then puncture, crush, or otherwise destroy before disposal in accordance with local regulations.
Do Not: Discharge wash water or residuals into the environment or drains.
Regulatory Codes: Check RCRA and local hazardous waste rules.
UN Number: UN1125
Proper Shipping Name: Butylamines, n.o.s. (includes 2-N-butylamine)
Hazard Class: 3 (Flammable liquid)
Packing Group: II
Label: Flammable liquid, Corrosive
Transport Precautions: Carry in upright, secure containers with compatible fittings. Keep away from sources of ignition or oxidizing agents.
Environmental Hazards: Marine pollutant
OSHA Status: Regulated as hazardous chemical
TSCA Listing: Yes
SARA Title III: Section 302 (not listed), Section 313 (not listed). Section 311/312: Fire, Acute health hazard
WHMIS (Canada): Class B2, D1B, E
REACH (EU): Registered substance under EC regulation 1907/2006
Other Information: This material requires careful documentation for workplace safety and environmental compliance.
