Nanjing Finechem Holding Co.,Limited
Knowledge


Material Safety Data Sheet: 19-Norprogesterone

Identification

Chemical Name: 19-Norprogesterone
Synonyms: 17β-Hydroxy-19-norpregn-4-en-3-one
CAS Number: 363-24-6
Product Code: Lab-grade sample, research use
Recommended Uses: Laboratory chemical, pharmaceutical intermediate
Supplier: Local laboratory or chemical supplier’s information to be filled in
Emergency Phone: Provider-specific emergency contact

Hazard Identification

GHS Classification: Not classified as hazardous under GHS; handle with care as health impacts can be difficult to assess
Hazard Statements: May cause mild skin or eye irritation; ingestion or inhalation should be avoided
Precautionary Statements: Avoid direct contact, ingesting, or breathing dust or powder; use in a well-ventilated space
Signal Word: None specified, general caution necessary
Health Hazards: Unknown if effects are cumulative or persistent with long-term exposure

Composition / Information on Ingredients

Chemical Name: 19-Norprogesterone
Common Name: 19-Norprogesterone
Concentration: 98-100% (may vary by source)
Impurities: Trace steroids or related compounds possible at low concentrations
Molecular Formula: C20H28O2
Molecular Weight: 300.44 g/mol

First Aid Measures

Inhalation: Move to fresh air, rest as necessary, medical consultation recommended for ongoing discomfort
Skin Contact: Immediately wash exposed skin with soap and water, remove contaminated clothing, seek attention for irritation
Eye Contact: Rinse eyes gently with water for several minutes; if discomfort doesn’t resolve, consult an eye doctor
Ingestion: Rinse mouth, do not induce vomiting; medical assessment recommended
Advice for Medical Staff: Provide symptomatic support, no specific antidote known

Fire-Fighting Measures

Suitable Extinguishing Media: Dry chemical powder, CO2, or foam; avoid using a direct stream of water
Unsuitable Media: Avoid water as a jet stream to prevent spreading material
Specific Hazards: Combustion can release carbon monoxide, carbon dioxide, other organic fumes
Protective Equipment: Wear self-contained breathing apparatus and full protective gear
Firefighting Tactics: Prevent runoff from entering drains or waterways, cool closed containers exposed to fire with water fog

Accidental Release Measures

Personal Precautions: Ventilate area, avoid dust formation, wear gloves, goggles, and protective clothing
Environmental Precautions: Keep from entering drains or environment, contain spill with inert material
Clean-Up Methods: Sweep up and place in designated closed container for disposal, avoid creating airborne dust
Decontamination: Wash area with plenty of soap and water

Handling and Storage

Safe Handling: Use local exhaust, keep container tightly closed, avoid inhalation or contact
Hygiene Measures: Wash hands thoroughly after handling, do not eat or drink in working space
Storage Conditions: Store in cool, dry, well-ventilated area, away from sunlight
Incompatible Materials: Strong oxidizing agents
Storage Class: Standard chemical store — pharmaceuticals or steroids section

Exposure Controls and Personal Protection

Engineering Controls: Use fume hood or local exhaust ventilation
Eye Protection: Chemical safety goggles
Skin Protection: Lab coat, dedicated gloves (nitrile or equivalent)
Respiratory Protection: Use mask if airborne concentration increases or dust is likely
Workplace Monitoring: General practice, avoid inhaling or ingesting dust
Personal Hygiene: Remove and wash contaminated clothing before reuse

Physical and Chemical Properties

Appearance: White to off-white solid powder
Odor: Odorless or very faint characteristic odor
pH: Not applicable (insoluble in water)
Melting Point: 161–165°C
Boiling Point: Not available (decomposes before boiling)
Solubility: Insoluble in water, soluble in organic solvents like methanol, ethanol, chloroform
Vapor Pressure: Not significant at room temperature
Density: Approx. 1.1–1.2 g/cm³
Partition Coefficient (Log Kow): Estimated; not experimentally determined
Flash Point: Not available

Stability and Reactivity

Chemical Stability: Remains stable under normal temperature and storage
Thermal Decomposition: Generates carbon oxides if overheated or burned
Conditions to Avoid: Excess heat, open flame, strong oxidizers
Reactivity: Non-reactive in standard laboratory settings
Hazardous Products of Decomposition: Releases hazardous carbon monoxide, carbon dioxide, potentially other organic compounds

Toxicological Information

Routes of Entry: Skin, eyes, inhalation, ingestion
Acute Effects: Minor irritation likely; long experience has not linked acute toxicity with normal handling
Chronic Effects: Unknown for casual lab exposure; some progestogenic steroids can affect hormone balance
LD50 (oral, rat): Not publicly available
Carcinogenicity: No evidence in animal or human studies
Reproductive Toxicity: Potential hormonal effects; animal data suggest possible interference with hormone cycles
Irritation: Not classified as a skin or eye irritant, yet washing off contamination promptly is strongly advised

Ecological Information

Ecotoxicity: Not well characterized in aquatic or terrestrial ecosystems
Persistence: Steroid structure may resist rapid degradation
Bioaccumulation Potential: Possible in aquatic organisms but not documented
Mobility in Soil: Binds to organic material, limited movement in groundwater
Other Information: Dispose responsibly; avoid uncontrolled environmental release

Disposal Considerations

Waste Treatment Methods: Gather residues, package securely, and send to hazardous waste disposal
Contaminated Containers: Rinse and dispose of following chemical waste protocols
Local Requirements: Follow health authority or environmental agency guidelines
Environmental Impact: Designed for lab use — not for drain, landfill, or open combustion

Transport Information

UN Number: Not classified as a dangerous good for transport
Proper Shipping Name: Chemicals, non-hazardous
Packing Group: None assigned
Transport Hazard Class: Not regulated
Special Precautions: Keep dry; avoid rough handling; secure packaging to prevent spills or dust

Regulatory Information

Federal Regulation: No specific restrictions for 19-Norprogesterone in small laboratory quantities
State Standards: May fall under local reporting or laboratory management guidelines
Workplace Classification: For research and laboratory use only; not therapeutically approved
Labeling: Identify as a steroidal research chemical on outer package
SARA/OSHA: Not listed as hazardous