Product Name: 19-Norpregn-4-Ene-3,20-Dione
Synonyms: Nandione, Estradione, Norandrostenedione
CAS Number: 601-63-8
Molecular Formula: C18H24O2
Recommended Use: Laboratory research, chemical synthesis
Manufacturer Details: [Company Name], [Address], [Contact Number]
Emergency Contact: [Emergency Phone Number / Poison Control]
GHS Classification: Acute Toxicity (oral, Category 4); Skin Irritation (Category 2); Eye Irritation (Category 2A)
Signal Word: Warning
Hazard Statements: Harmful if swallowed; causes skin and eye irritation; may cause reproductive toxicity based on animal data
Precautionary Statements: Wear protective gloves, avoid breathing dust, wash exposed skin thoroughly after handling, do not eat/drink/smoke when using the material
Pictograms: Exclamation mark, Health hazard
Chemical Name: 19-Norpregn-4-Ene-3,20-Dione
CAS Number: 601-63-8
Concentration: >98% pure
Impurities: Trace residual solvents or byproducts may be present in research-grade batches
Inhalation: Remove person to fresh air, keep at rest, seek medical help if symptoms persist
Skin Contact: Wash affected skin immediately with plenty of soap and water, remove contaminated clothing, consult a doctor if irritation continues
Eye Contact: Rinse eyes slowly and gently with water for at least 15 minutes, lift eyelids to ensure thorough rinsing, get medical attention as needed
Ingestion: Rinse mouth, do not induce vomiting, give water if person is conscious, consult physician right away
Most Important Symptoms: Skin redness, burning in eyes, sore throat, stomach upset if swallowed
Suitable Extinguishing Media: Dry chemical, carbon dioxide, water spray, foam
Special Hazards: Dust can form explosive mixtures in air, thermal decomposition may release irritating fumes like carbon oxides
Protective Equipment: Firefighters should wear self-contained breathing apparatus and full protective gear
Advice: Avoid breathing smoke, control runoff to prevent environmental contamination
Personal Precautions: Put on protective gear, prevent dust formation, avoid contact with skin or eyes
Environmental Precautions: Prevent powder from entering drains, soil, or waterways
Methods for Clean-up: Scoop up powder carefully, avoid generating dust, store in closed waste containers for proper disposal, ventilate the area well after cleanup
Handling: Use in well-ventilated space, open containers slowly, avoid generation of airborne dust, wash hands after handling, keep away from food, drink, and animal feed
Storage: Store in tightly closed containers, keep away from heat, light, and moisture, place containers in a dry, cool, and well-ventilated space with secure shelving
Exposure Limits: Not established specifically for this compound—observe good laboratory hygiene
Engineering Controls: Use local exhaust ventilation to minimize exposure, handle inside fume hood if possible
Personal Protective Equipment: Chemical-resistant gloves, lab coat, safety goggles; for large-scale work, use a respirator rated for organic dusts
Hygiene: No eating, drinking, or smoking in working area, wash hands thoroughly before breaks and after handling
Appearance: Off-white to pale yellow crystalline powder
Odor: Odorless
Melting Point: 162–166°C
Boiling Point: Not established due to decomposition
Solubility: Insoluble in water, soluble in ethanol, dimethyl sulfoxide (DMSO)
Vapor Pressure: Negligible under ambient conditions
Relative Density: 1.18–1.20 g/cm³
Other Properties: Stable in dry air, sensitive to strong oxidizers
Chemical Stability: Stable under recommended storage conditions
Incompatibilities: Avoid strong acids, bases, oxidizing agents
Decomposition Products: May yield carbon monoxide, carbon dioxide, and other organic fumes on combustion or decomposition
Reactivity: Not reactive with most common laboratory materials
Polymerization: Does not occur under normal conditions
Routes of Entry: Inhalation, ingestion, skin contact, eye contact
Acute Effects: May cause gastrointestinal upset, skin and eye irritation, headache, or dizziness
Chronic Effects: Based on similar compounds, possible endocrine disruption, effects on reproductive health with repeated exposure
Carcinogenicity: No IARC, NTP, or OSHA classification for cancer risk
LD50/LC50: Not fully characterized; similar steroids have moderate toxicity in rodents
Other Risks: Allergic skin reactions with repeated exposure in sensitive individuals
Persistence and Degradability: Not easily biodegradable, may persist in environment
Bioaccumulation: Potential for accumulation in aquatic organisms if released into water
Ecotoxicity: Data limited, but hormones and steroidal compounds may impact aquatic life even at low concentrations
Wastewater Impact: Avoid discharge into waterways, use secondary containment to limit environmental exposure
Disposal Methods: Collect waste in sealed containers, avoid landfill, incinerate in authorized facility
Contaminated Packaging: Rinse and treat as hazardous waste, dispose of according to local, state, and federal regulations
Sewage Disposal: Not permitted, must not pour down drains or into public water systems
Waste Codes: Assign based on local authorities if applicable
UN Number: Not assigned
Proper Shipping Name: Chemical Substance, not otherwise specified
Transport Hazard Class: Not regulated under UN, ADR, IATA, or IMDG for small laboratory quantities
Packing Group: Not applicable
Special Precautions for Transportation: Protect containers from breakage, keep tightly sealed and upright during transport
TSCA Status: Research use only, not listed for commercial use in US
Canada DSL/NDSL: Not listed
EU Regulations: May be subject to REACH requirements as an endocrine disruptor
SARA 313: Not listed
State Regulations: Not listed on California Proposition 65; local regulations may apply for handling hormone-active chemicals
