Nanjing Finechem Holding Co.,Limited
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Material Safety Data Sheet: 19-Norandrosterone

Identification

Product Name: 19-Norandrosterone
Chemical Family: Androgenic steroid metabolite
Synonyms: 5α-Estran-3α-ol-17-one
CAS Number: 113-40-8
Intended Use: Laboratory research, reference standard
Manufacturer: Listed supplier information per lab procurement
Contact Information: Local supplier, laboratory manager, or university EHS office
Emergency Hotline: CHEMTREC: 1-800-424-9300, local medical contacts

Hazard Identification

Hazard Class and Category: Not listed as hazardous under GHS classification, but significant health risks noted with exposure
Route of Exposure: Inhalation, ingestion, skin contact, eye contact
Signal Word: Warning
Symptoms: Respiratory tract irritation, minor skin redness, possible hormonal disturbances on repeated contact, eye irritation
Pictograms: GHS07 (exclamation mark), consult safety officer for updates
Other Hazards: Laboratory use may present elevated risk due to hormonal activity, bioaccumulation possible with spills
Precautionary Statements: Proper PPE, fume hood use, avoid all unnecessary exposure, no eating or drinking near sample

Composition / Information on Ingredients

Chemical Identity: 19-Norandrosterone
Purity: >98% (Vendor batch sheet specifies exact lot analysis)
Impurities: Trace androgenic steroids, residual solvents may be present at very low levels
EINECS Number: 204-043-6
Hazard Ingredients: No additives or non-intended ingredients declared

First Aid Measures

Inhalation: Remove person from exposure, ensure fresh air, support breathing, seek medical advice especially if symptoms persist
Skin Contact: Remove contaminated clothing, wash skin with mild soap and plenty of water for 15 minutes, consult physician if irritation or hormonal changes noticed
Eye Contact: Rinse eyes under gentle running water for at least 15 minutes, keep eyelids open, consult medical attention if redness or pain persists
Ingestion: Rinse mouth, do not induce vomiting, seek immediate medical attention
Advice for Doctor: Supportive care, monitor hormone panel if significant quantity suspected

Fire-Fighting Measures

Suitable Extinguishing Media: Water spray, CO2, dry chemical, foam
Special Hazards: Combustion may release smoke, carbon oxides, possible hazardous decomposition
Protective Equipment: Self-contained breathing apparatus, full protective suit
Additional Info: Avoid inhalation of combustion products, remove containers from fire area if safe
Cool Exposed Containers: Use water spray to keep containers cool and reduce risk of spatter

Accidental Release Measures

Personal Precautions: Evacuate area, ventilate, wear PPE—lab coat, gloves, safety glasses or face shield
Containment: Avoid dust formation, avoid direct contact with spilled material, block larger spills
Cleanup: Scoop up solids with minimal dust, place in labeled, sealable container, clean area with approved detergent, dispose as chemical waste
Disposal of Contaminated Material: Place absorbent and cleanup towels in hazardous waste bag
Reporting: Report significant releases to EHS or regulatory authorities as required

Handling and Storage

Handling: Work in well-ventilated space or fume hood, use standard laboratory safety practices, keep away from food, drink, and incompatible materials
Personal Hygiene: Wash hands after handling, keep gloves disposable and change if contaminated
Storage: Store in tightly closed container at 2-8°C (refrigerator), dry area, protect from light and moisture, segregation from oxidizers
Secure Access: Restrict storage to authorized users, label clearly with content and hazard

Exposure Controls and Personal Protection

Occupational Exposure Limits: No established OSHA/ACGIH limits, handle as hazardous
Engineering Controls: Fume hoods, low-dust techniques, minimize open transfer
Respiratory Protection: NIOSH-approved mask if powder dust likely
Eye Protection: Laboratory goggles or safety glasses with side shields
Skin Protection: Nitrile or latex gloves, lab coats, closed footwear
Environmental Protection: Prevent entry into drains or natural water

Physical and Chemical Properties

Appearance: White to off-white crystalline powder
Odor: Odorless
pH: Not applicable in solid form
Melting Point: 183-185°C
Boiling Point: Not available—chemical decomposes
Solubility: Slightly soluble in water, soluble in ethanol, DMSO, methanol
Flash Point: Not determined
Vapor Pressure: Very low
Partition Coefficient: High tendency to bioaccumulate in fatty tissue (log P > 3)
Density: 1.15–1.17 g/cm3

Stability and Reactivity

Stability: Stable at recommended storage conditions, sensitive to light and moisture
Reactivity: No significant reactivity under standard lab conditions
Conditions to Avoid: Prolonged exposure to air, humidity, elevated temperature
Incompatible Materials: Strong oxidizing agents, strong acids
Decomposition Products: Carbon monoxide, carbon dioxide, possible low-molecular degradation products on combustion

Toxicological Information

Acute Toxicity: Not fully studied in humans; animal studies indicate hormonal activity at low doses, not acutely toxic by oral or inhalation route
Chronic Effects: Endocrine disruption, reproductive effects, possible hepatic strain on repeated exposure
Sensitization: No data, but adhere to caution with all steroids
Carcinogenicity: Not classified as carcinogen by IARC or NTP
Additional Risks: Hormone-responsive individuals may be more sensitive, follow strict exposure limits in reproductive age
Mutagenicity: Not observed in standard assays, but data limited

Ecological Information

Ecotoxicity: Not highly soluble, but bioactive in water organisms, disrupts hormonal cycles in aquatic species
Persistence and Degradability: Does not degrade rapidly, risk extends with continuous input
Bioaccumulation: Likely, based on physical partition data
Mobility: Poor—adheres to soils, sediment, organic matter
Avoid Release: Critical to contain all spills, prevent entry to water systems
Regulations: Controlled substance status in many countries, improper disposal may violate water protection laws

Disposal Considerations

Disposal Method: Incinerate in licensed chemical facility
Waste Classification: Treat as hazardous organic chemical waste
Container Cleaning: Triple rinse, send all residues for chemical waste
Disposal Precaution: Never flush to sewer, avoid dust, label as hormone-active
Consult: Local EHS, observe state and federal disposal laws

Transport Information

UN Number: Not assigned for small research use quantities
Proper Shipping Name: Laboratory chemical, N.O.S.
Hazard Class: Not regulated for transport under normal quantities
Packing Group: Not assigned
Special Precautions: Keep packaging tightly closed, ship in secondary containment, avoid temperature extremes
International Regulations: Controlled substance under WADA, consult shipping company and customs

Regulatory Information

US TSCA Status: Not listed for unrestricted use
EU REACH Status: Not registered, use subject to special lab status
Controlled Substance: Subject to doping control, handle with permission
Workplace Labelling: Comply with OSHA Hazard Communication, supply SDS to users
Other Regulations: Research use only, observe institutional guidelines, monitor for updates on regulatory listings