Product Name: 19-Nor-Doxercalciferol
Chemical Formula: C27H44O2
Synonyms: 19-Norvitamin D2, 19-Nor-1,25-dihydroxyvitamin D2
Manufacturer: Enter name, address, and emergency contact of supplier or manufacturer here
Recommended Use: Research and pharmaceutical development, not for human or veterinary drug use without proper licensing
Emergency Contact: Provide emergency phone number
GHS Classification: Acute toxicity (oral, dermal, inhalation); Skin irritant; Eye irritant
Signal Word: Warning
Hazard Statements: May cause respiratory irritation; May be harmful if swallowed or inhaled; Causes skin and eye irritation
Precautionary Statements: Avoid breathing dust; Wear protective clothing and gloves; Wash thoroughly after handling; Handle in a well-ventilated area
Potential Health Effects: May cause hypercalcemia, irritation to skin, eyes and respiratory tract; possible symptoms of overexposure include nausea, vomiting, headache, and muscle weakness
Hazards Not Otherwise Classified: Environmental exposure risk in large quantities
Chemical Name: 19-Nor-Doxercalciferol
CAS Number: 69851-42-9
Concentration: 95 – 100%
Impurities/Additives: None present in significant quantities
Eye Contact: Rinse cautiously with water for several minutes; remove contact lenses if present and easy to do; continue rinsing; seek medical attention if irritation persists
Skin Contact: Wash with plenty of soap and water; remove contaminated clothing; obtain medical attention for persistent irritation
Inhalation: Move to fresh air; provide oxygen if breathing is difficult; seek medical help if symptoms do not resolve
Ingestion: Rinse mouth thoroughly; do not induce vomiting unless directed by medical personnel; consult a physician
Most important symptoms/effects: May include gastrointestinal upset, altered consciousness, or symptoms related to hypercalcemia
Advice to Physician: Treat symptomatically and provide supportive care
Suitable Extinguishing Media: Use water spray, carbon dioxide, dry chemical powder, or foam
Specific Hazards: The compound does not burn easily, but thermal decomposition may produce irritating or toxic fumes, including oxides of carbon
Protective Equipment for Firefighters: Wear self-contained breathing apparatus and full protective clothing
Special Procedures: Prevent runoff from entering drains or water sources
Personal Precautions: Use appropriate personal protective equipment (PPE); avoid breathing dust; ensure adequate ventilation
Spill Response: Sweep up gently using non-sparking tools and transfer to a labeled waste container; avoid creating dust; do not allow spills to enter water or drains
Environmental Precautions: Prevent further leakage; avoid contamination of soil, waterways, or drains by containing and collecting spillage
Handling: Use only in well-ventilated areas; minimize dust generation and accumulation; use personal protective equipment as required; keep containers tightly closed; wash hands after use
Storage: Store locked up in a tightly sealed container away from direct sunlight, moisture, and incompatible substances, at 2–8°C or as indicated by manufacturer; keep away from food and drink
Incompatibilities: Strong oxidizers, acids, or bases may react with product
Exposure Limits: No OSHA or ACGIH exposure limits established; minimize exposure as a precaution
Engineering Controls: Use local exhaust or general ventilation to control exposure
Personal Protective Equipment: Wear splash-proof safety goggles, chemical-resistant gloves, laboratory coat; use dust respirator if ventilation is inadequate; never eat or drink while working with product
Appearance: White to off-white powder or crystalline solid
Odor: Odorless
Odor Threshold: Not applicable
pH: Not applicable
Melting Point/Freezing Point: Approx. 185–195°C (decomposes)
Boiling Point: Not available (decomposes before boiling)
Flash Point: Not determined
Evaporation Rate: Not determined
Flammability: Not flammable
Vapor Pressure: Not applicable
Vapor Density: Not applicable
Solubility: Insoluble in water; soluble in organic solvents
Partition Coefficient: Not determined
Auto-ignition Temperature: Not determined
Decomposition Temperature: Data not available
Viscosity: Not applicable
Chemical Stability: Stable under recommended storage conditions
Reactivity: Minimal for intended use
Possibility of Hazardous Reactions: Strong oxidizers may cause reactions; avoid moisture
Conditions to Avoid: Direct sunlight, excess heat, open flames, and humidity
Incompatible Materials: Strong acids, bases, oxidizing agents
Hazardous Decomposition Products: May yield toxic fumes such as carbon oxides under fire or thermal decomposition
Route of Exposure: Inhalation, ingestion, skin, or eye contact
Acute Toxicity: Data is limited. Potential for toxicity primarily from vitamin D overdose effects, such as hypercalcemia
Chronic Effects: Risk of hypercalcemia and related organ damage due to prolonged or high exposure
Symptoms of Overexposure: Nausea, vomiting, constipation, weakness, dehydration, confusion (consistent with hypercalcemia); skin or eye irritation possible
Sensitization: No data
Carcinogenicity: Not listed by NTP, IARC, or OSHA
Mutagenicity: Not known
Reproductive Toxicity: Data not sufficient
Ecotoxicity: May have adverse effects on aquatic organisms in high concentrations due to persistence and bioaccumulation
Persistence and Degradability: Likely persistent in environment; limited biodegradability
Bioaccumulative Potential: Potential to bioaccumulate due to lipophilic nature
Mobility in Soil: Low mobility in soil expected
Other Adverse Effects: Avoid uncontrolled environmental release
Disposal Methods: Dispose of product in accordance with local, regional, and national regulations; place in a suitable sealed container for chemical waste; do not release to environment
Contaminated Packaging: Triple rinse containers; dispose by controlled incineration or at licensed landfill facility
Special Considerations: Use registered waste carrier; prevent unauthorized disposal
UN Number: Not regulated for transport
UN Proper Shipping Name: Not regulated
Transport Hazard Class: Not applicable
Packing Group: Not applicable
Marine Pollutant: No data; avoid release to water
Special Precautions: Avoid transit with chemicals that are incompatible
TSCA Status: Not listed for public sale or use; research chemical
DSL/NDSL (Canada): Not listed
SARA Title III Sections 302/304, 311/312, 313: Not subject
California Proposition 65: Not listed
EU Regulations: Not classified as dangerous under current regulations; use restriction applies for pharmaceuticals
Other Requirements: Handle in accordance with recognized good laboratory and manufacturing practices
