Nanjing Finechem Holding Co.,Limited
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Material Safety Data Sheet (MSDS): 19-Nor-5-Androstenediol

Identification

Product Name: 19-Nor-5-Androstenediol
Chemical Family: Steroidal compound
SYNONYMS: Estr-5-ene-3β,17β-diol
CAS Number: 521-17-5
Recommended Use: Research, laboratory analysis
Manufacturer Information: [Insert Company Name, Address, Phone, Emergency Contact Number]

Hazard Identification

GHS Classification: Eye Irritant, Skin Sensitizer, Reproductive Toxicant
Signal Word: Danger
Hazard Statements: Causes skin irritation, may cause allergic reactions, suspected of damaging fertility or the unborn child, harmful if swallowed
Precautionary Statements: Avoid touching skin and eyes, avoid inhalation or ingestion, use only with adequate ventilation, wear gloves and protective clothing
Emergency Overview: Powdered steroid, white to off-white, no significant odor, can irritate skin/eyes or disrupt hormones

Composition / Information on Ingredients

Chemical Name: 19-Nor-5-Androstenediol
Common Name: Steroid prohormone
CAS Number: 521-17-5
Purity: >98% (typical for research grade)
Impurities: Trace related steroidal compounds (<2%)
Formulation: Pure substance, not part of a mixture

First Aid Measures

Eye Contact: Rinse thoroughly with plenty of clean water for at least 15 minutes, keep eyelids open, remove contact lenses if present, seek urgent medical advice if redness or irritation persists
Skin Contact: Wash with mild soap and water, remove contaminated clothing, pay attention to skin changes, consult a physician if irritation continues
Inhalation: Move to fresh air immediately, check breathing, offer oxygen if breathing is difficult, consult medical personnel if symptoms develop
Ingestion: Rinse mouth thoroughly, never induce vomiting, provide water to drink if the person is alert, get medical help right away
Symptoms: Redness, itching, burning sensation, hormone-related effects with significant exposure

Fire-Fighting Measures

Flammability: May be combustible in powder form, does not present high fire hazard under typical storage
Suitable Extinguishing Media: Dry chemical, carbon dioxide, foam, water spray for large fires
Unsuitable Extinguishing Media: High-pressure water jets (may spread dust)
Special Hazards: May produce toxic fumes of carbon oxides and steroidal decomposition products under intense fire
Protective Equipment: Self-contained breathing apparatus and full protective gear
Firefighting Instructions: Isolate area, cool surrounding containers with water spray

Accidental Release Measures

Personal Precautions: Keep unnecessary persons away, avoid dust, ventilate area well, put on gloves, eye shield, and dust mask
Environmental Precautions: Prevent release to water systems, do not allow runoff into drains
Clean-Up Methods: Sweep up solid powder with minimum dust, use damp paper or HEPA vacuum for residues, collect in suitable closed container for disposal, wash affected surface with soap and water
Spill Size Response: For small spills, use wipe-up and disposal procedure; for large releases, contact safety specialist and follow local protocols

Handling and Storage

Safe Handling: Operate in a well-ventilated area, avoid direct contact with powder, wash hands after use, keep containers tightly closed
Incompatible Materials: Strong oxidizers, acids, extreme heat sources
Technical Measures: Use personal protective equipment, handle away from food or beverages
Storage Requirements: Store in cool, dry place, temperature between 2-8°C recommended, protect from sunlight, keep in original packaging, restrict access
Special Conditions: Store separate from hormone-sensitive materials and out of general traffic zones

Exposure Controls and Personal Protection

Engineering Controls: Use chemical fume hood or local exhaust ventilation to minimize airborne particles
Exposure Limits: No OSHA or ACGIH exposure limits established, prudent avoidance advised
Protective Equipment: Nitrile gloves, lab coat, safety glasses with side shields or goggles, particle mask or respirator for dust work
Hygiene Measures: Do not eat, drink, or smoke in work area, wash exposed skin after use, discard contaminated clothing safely
Environment Controls: Prevent environmental discharge, use closed-system equipment when possible

Physical and Chemical Properties

Appearance: White to off-white crystalline powder
Odor: Odorless
Melting Point: 143–147°C
Boiling Point: Not available
Solubility: Insoluble in water, soluble in organic solvents (ethanol, DMSO)
Vapor Pressure: Negligible at room temperature
Particle Size: Fine powder
pH: Not applicable (non-aqueous solid)
Density: Approx. 1.1 g/cm³
Flash Point: Not determined, not expected to present significant flammability

Stability and Reactivity

Chemical Stability: Stable under standard handling and storage conditions
Decomposition: High temperature or fire may produce carbon oxides, toxic fumes
Incompatible Substances: Strong oxidizing acids, reducing agents
Reactivity: No hazardous polymerization, remains inert unless mixed with reactive chemicals
Storage Requirements: Avoid prolonged exposure to light, heat, or humidity; keep well-sealed containers
Special Hazards: Dust can accumulate and increase exposure risk

Toxicological Information

Acute Toxicity Data: Oral/dermal toxicity not fully established; avoid direct contact or ingestion
Chronic Exposure: Known to disrupt endocrine systems, possible reproductive toxicity
Routes of Entry: Skin, eyes, inhalation of dust, ingestion
Symptoms: Irritation, allergic skin reaction, headache, hormonal effects such as mood changes, reproductive risks
Carcinogenicity: No regulatory listing, long-term effects not fully studied
Sensitization: May cause allergy or hormone sensitivity in susceptible individuals

Ecological Information

Aquatic Toxicity: Not well documented; avoid contamination of waterways
Environmental Fate: Not expected to biodegrade quickly in soil or water
Bioaccumulation: Possible due to steroid structure, could impact aquatic organisms
Mobility: Limited by low water solubility; could adhere to soils or sediments
Best Practices: Do not release untreated to the environment, always use specialized disposal channels

Disposal Considerations

Waste Handling: Treat as hazardous laboratory chemical; use sealed, labeled containers
Disposal Methods: Incinerate under controlled conditions or take to hazardous waste facility permitted to process hormone-active substances
Regulations: Comply with local, state, and national chemical waste laws
Special Instructions: Do not dispose in regular trash or drains, segregate and document all disposals
Packaging: Seal waste in double-bagged, clearly labeled containers for pick-up by authorized disposal contractor

Transport Information

Shipping Name: 19-Nor-5-Androstenediol
UN Number: Not assigned
Hazard Class: Not specifically regulated for transport; treat as laboratory chemical
Packaging Requirements: Well-sealed, leak-proof containers, secondary containment if required
Transport Precautions: Avoid rough handling, restrict temperature extremes, document chain of custody
Emergency Response: Use PPE for first responders, refer to SDS in case of spillage during transport

Regulatory Information

Regulatory Status: Not listed on major controlled substance schedules; may fall under sports anti-doping or pharmaceutical regulations
SARA/OSHA Status: Not an OSHA hazardous chemical; not subject to SARA reporting
REACH Status: No registration known, consult European directives for current status
State/Local: Check any local health, university, or sports authority restrictions
Labeling Requirements: Labelling by workplace and transport regulations, include hazard pictograms and wording as per CLP/GHS
Worker Safety: Users should review training and hazard review before handling any research steroidal product