Product Name: 19-Nor-5-Androstenedione
Chemical Formula: C18H24O2
Synonyms: Estr-4-ene-3,17-dione
CAS Number: 734-32-7
Recommended Use: Laboratory reagent, reference material
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GHS Classification: Reproductive toxicity, Eye irritation, Target organ toxicity
Signal Word: Warning
Hazard Statements: Suspected of damaging fertility; May cause skin and eye irritation; Inhalation may affect hormonal balance
Pictograms: Exclamation mark, Health hazard
Precautionary Statements: Avoid breathing dust; Wear gloves and eye protection; Wash thoroughly after handling
Chemical Name: 19-Nor-5-Androstenedione
CAS Number: 734-32-7
Concentration: >98%
Impurities: Less than 1.5% total, primarily related steroidal compounds
Inhalation: Move outside into fresh air; support breathing if needed; consult a physician after exposure
Skin Contact: Remove contaminated clothing; rinse skin with plenty of water; seek medical advice for persistent irritation
Eye Contact: Rinse eyes under running water for 15 minutes, keeping eyelids open; seek medical evaluation if discomfort remains
Ingestion: Rinse mouth thoroughly; drink water; avoid provoking vomiting; seek immediate medical attention
Suitable Extinguishing Media: Dry chemical powder, CO2, foam
Unsuitable Extinguishing Media: Avoid high-pressure water streams which might spread material
Hazardous Combustion Products: Carbon monoxide, carbon dioxide, potentially irritating fumes
Protective Equipment: Full protective gear and self-contained breathing apparatus for large scale incidents
Firefighting Procedures: Stay upwind; prevent runoff from contaminating waterways
Personal Precautions: Stay clear of dust; ventilate area; restrict access to exposed site
Environmental Precautions: Block further leakage if safe; keep material out of water systems
Cleanup Methods: Use non-sparking tools to collect spilled powder; place into labeled sealed containers for disposal; wash area with water and detergent after bulk cleanup; ventilate affected space
Handling: Work in a chemical fume hood; avoid skin and eye contact; do not eat or drink near work area; keep containers tightly sealed
Storage: Store in a cool, well-ventilated area, away from strong oxidizers and direct sunlight; keep container tightly closed; avoid sources of ignition; store only in original container with appropriate labeling
Incompatibilities: Strong acids, strong bases, oxidizing agents
Engineering Controls: Use local exhaust ventilation; handle inside chemical hood whenever possible
Eye Protection: Chemical safety goggles with side shields
Skin Protection: Gloves made of nitrile or other chemical-resistant barrier materials; lab coat or apron
Respiratory Protection: Dust mask or cartridge respirator for particulate if airborne concentrations rise
Exposure Limits: No established occupational exposure limits for this substance; minimize exposure by industrial hygiene controls
Appearance: White to pale yellow crystalline powder
Odor: Essentially odorless
Molecular Weight: 272.4 g/mol
Melting Point: 155 – 158°C
Boiling Point: Data not available; decomposes before boiling
Solubility: Slightly soluble in water; soluble in ethanol, chloroform, acetone
pH: Not applicable (solid form)
Vapor Pressure: Negligible at room temperature
Flash Point: Not established; avoid open flames
Chemical Stability: Stable under recommended conditions
Reactivity: No hazardous reactions under normal storage and handling
Incompatible Materials: Strong acids, bases, oxidizers
Hazardous Decomposition: Carbon monoxide, carbon dioxide, smoke, and irritating organic vapors
Conditions to Avoid: Excessive heat, sunlight, moisture, and flames
Likely Routes of Exposure: Inhalation, skin, eyes, ingestion
Acute Effects: May cause mild to moderate irritation upon contact with eyes or skin; inhalation of large amounts may irritate upper respiratory tract
Chronic Effects: Suspected endocrine disruption, reproductive system effects; long-term or repeated exposure might interfere with hormonal health
Symptoms of Overexposure: Skin or eye redness, headache, nausea, potential symptoms of hormonal imbalance
Carcinogenicity: Not classified as carcinogenic by IARC, NTP, or OSHA
Other Data: No definitive reproductive or teratogenic data for humans, but steroidal compounds may alter endocrine function on significant or repeated exposure
Aquatic Toxicity: Not thoroughly studied; steroidal substances may disrupt aquatic species’ endocrine systems
Persistence and Degradability: Uncertain; may persist in soil and sediment
Mobility in Soil: Tends to bind to solids; limited mobility in clean water
Bioaccumulation: Data not available, steroids in general have potential for bioaccumulation
Other Adverse Effects: Release into water may interfere with reproductive health of aquatic organisms; care needed to avoid even small spills
Waste Treatment Methods: Dispose as hazardous chemical waste per local, state, and federal laws; keep out of sewage and natural water routes
Contaminated Packaging: Triple rinse, then dispose with chemical waste if possible
Special Precautions: Wear suitable protection during disposal handling
UN Number: Not regulated as a dangerous good under transport regulations
Transport Hazard Class: Not assigned
Packing Group: Not assigned
Environmental Hazards: None established, though prudent to protect from release
Proper Shipping Name: Chemicals, N.O.S. (if required in significant quantity)
Special Precautions: Secure container tightly; avoid rough handling; keep away from incompatible cargo
US Federal: Not listed specifically under TSCA; laboratory use may fall under research exemptions
EU Regulations: May fall under REACH or similar regulation as an endocrine-active substance; authorization may be limited
Canada: Not listed on DSL/NDSL
Other National Inventories: Consult local authorities for country-specific regulations
Labeling Requirements: Chemical hazard labels, laboratory signage, and restricted access according to local chemical safety policy
