Product Name: 19-Nor-4-Androstenedione
Other Names: Estr-4-ene-3,17-dione; Norandrostenedione
CAS Number: 734-32-7
Recommended Use: Laboratory chemical, research and development use only
Restrictions on Use: Not for drug, household, or other uses
Manufacturer/Supplier: [Insert chemical supplier name and contact details]
Emergency Contact: [Insert emergency telephone number]
Classification: Acute toxicity (oral and dermal – category 4), Eye irritation (category 2), Specific target organ toxicity (single exposure – category 3), Reproductive toxicity (category 2)
Signal Word: Warning
Hazard Statements: Harmful if swallowed. Harmful in contact with skin. Causes serious eye irritation. Suspected of damaging fertility or the unborn child. May cause respiratory irritation.
Pictograms: Exclamation mark, Health hazard
Precautionary Statements: Do not breathe dust or mist. Wash hands thoroughly after handling. Use only outdoors or in a well-ventilated area. Wear protective gloves, protective clothing, and eye protection. If in eyes: rinse cautiously with water for several minutes.
Chemical Name: 19-Nor-4-Androstenedione
Synonyms: Estr-4-ene-3,17-dione
CAS Number: 734-32-7
EC Number: 211-274-2
Concentration: ≥98% (pure compound); may contain minimal residual impurities due to synthesis or packaging
Inhalation: Move person out of exposure area. Seek fresh air. Provide oxygen if breathing is labored. Get medical attention if symptoms emerge.
Skin Contact: Remove contaminated clothing and shoes. Wash skin with soap and water thoroughly. Get medical advice if irritation, redness, or symptoms persist.
Eye Contact: Rinse eyes carefully with plenty of water for at least 15 minutes. Hold eyelids apart during rinsing. Remove contact lenses if present and easy to do.
Ingestion: Rinse mouth with water. Do not induce vomiting. Seek medical help if swallowed or if feeling unwell.
Most Important Symptoms/Effects: Irritation to eyes, skin, upper respiratory tract. Can interfere with hormonal balance with repeated exposure.
Notes for Doctor: Treat symptomatically and supportively. Monitor hormonal levels in prolonged exposures.
Suitable Extinguishing Media: Carbon dioxide, dry chemical powder, water spray, alcohol-resistant foam
Unsuitable Extinguishing Media: Straight water jets
Special Hazards from Fire: May emit toxic fumes including carbon monoxide, carbon dioxide, nitrogen oxides
Protective Equipment: Wear self-contained breathing apparatus (SCBA) and full fire protective gear
Advice for Firefighters: Approach from upwind. Prevent runoff from fire control or dilution from entering streams, sewers, or drinking water supply
Personal Precautions: Use appropriate personal protective equipment such as gloves, goggles, lab coat. Avoid dust formation. Ventilate area.
Environmental Precautions: Prevent further leakage or spillage. Do not allow product to enter drains or water sources.
Cleanup Methods: Sweep up without generating dust. Place in suitable, closed containers for disposal. Clean contaminated area with soap and water after collection.
Safe Handling: Keep away from sources of ignition, strong acids, and strong bases. Avoid contact with skin, eyes, and clothing. Handle in a chemical fume hood if possible.
Storage Conditions: Store tightly closed in a dry, cool, well-ventilated area. Protect from light. Keep away from food and drink. Use lockable chemical cabinets for controlled substances.
Incompatible Materials: Strong oxidizers, acids, and bases
Occupational Exposure Limits: No established exposure limits; use minimal exposure practices
Engineering Controls: Use chemical fume hood, ensure adequate ventilation, safety showers, and eyewash stations nearby
Personal Protective Equipment:
Appearance: White to off-white crystalline powder
Odor: Odorless
Odor Threshold: Not applicable
pH: Not determined (sparingly soluble in water)
Melting Point/Freezing Point: 164–166°C (327–331°F)
Boiling Point: Data not available
Flash Point: Data not available (may not be flammable)
Evaporation Rate: Not applicable
Flammability: Not considered flammable in solid form
Upper/Lower Flammability or Explosive Limits: Not determined
Vapor Pressure: Negligible at room temperature
Vapor Density: Not applicable
Relative Density: Not established
Solubility: Slightly soluble in water, soluble in organic solvents (ethanol, DMSO)
Partition Coefficient (log Kow): Not available
Auto-ignition Temperature: Not available
Decomposition Temperature: Not established
Viscosity: Not applicable
Chemical Stability: Stable under recommended storage conditions
Reactivity: No reactive hazards under normal conditions
Hazardous Reactions: Strong oxidizing agents may cause combustion or decomposition
Decomposition Products: Carbon monoxide, carbon dioxide, nitrogen oxides
Conditions to Avoid: Heat, moisture, light
Incompatible Materials: Strong acids, bases, and oxidizing agents
Acute Toxicity: Data limited; suspected oral LD50 in rats > 2000 mg/kg
Skin Corrosion/Irritation: May cause irritation to sensitive skin
Serious Eye Damage/Irritation: May cause significant eye irritation
Respiratory or Skin Sensitization: Not enough data, but prolonged contact could cause sensitization in susceptible individuals
Mutagenicity: No available data; structurally similar compounds show low mutagenic risk
Carcinogenicity: No classification by IARC, NTP, or OSHA
Reproductive Toxicity: Experimental data indicate hormonal activity; potential negative effects on fertility and fetal development with repeated exposure
Specific Target Organ Toxicity (Single Exposure): Possible effects on endocrine and reproductive systems
Specific Target Organ Toxicity (Repeated Exposure): Repeated or prolonged exposure could disrupt hormonal balance
Ecotoxicity: Not expected to be highly toxic to aquatic life at low concentrations; possible endocrine disruption in aquatic organisms due to hormonal activity
Persistence and Degradability: Not readily biodegradable; may persist in environmental compartments for extended periods
Bioaccumulative Potential: Potential for bioaccumulation in aquatic organisms due to steroid structure
Mobility in Soil: Low water solubility decreases mobility; likely to adsorb to soils and sediments
Other Adverse Effects: Disruption of aquatic organism reproduction could occur in contaminated waters
Disposal Method: Dispose through licensed chemical waste disposal contractor. Avoid wastewater release.
Contaminated Packaging: Dispose as chemical waste. Triple rinse and puncture containers before disposal if permitted.
Special Considerations: Do not mix with household garbage. Keep out of sewage and drainage systems. Comply with relevant state, local, and national regulations.
UN Number: Not regulated as a hazardous material for transport
Proper Shipping Name: Not regulated
Transport Hazard Class: Not assigned
Packing Group: Not assigned
Marine Pollutant: Not classified as marine pollutant
Transport Precautions: Package securely to prevent leaks. Protect from extreme heat, moisture, or rough handling. Document laboratory use on shipping paperwork if applicable.
TSCA Status: Not listed or subject to reporting under the Toxic Substances Control Act
SARA Title III, Section 302/311/312: Not classified under extremely hazardous substances
California Proposition 65: Not listed
WHMIS (Canada): Not controlled
EU Regulation (REACH): May require registration for usage above thresholds
Controlled Substance Status: Controlled in some countries due to anabolic and hormonal activity
Other Regulations: Supplier and workplace health and safety requirements may apply—consult local, state, and national regulations.
