Product Name: 19-Nor-4-Androstenediol
Chemical Name: 17β-hydroxyestra-4-ene-3,17-diol
Synonyms: 19-Norandrostenediol, 19-Norandrost-4-ene-3β,17β-diol
CAS Number: 521-17-5
Molecular Formula: C18H26O2
Recommended Uses: Research laboratory use, chemical synthesis
Manufacturer Details: [Manufacturer Name], [Address], [Contact Phone], [Emergency Phone]
Classification: Non-scheduled substance, no major hazards identified for immediate acute exposure but may cause reproductive toxicity
GHS Label Elements: Signal word: Warning; Hazard statements: H361 – Suspected of damaging fertility or the unborn child
Pictograms: Health hazard symbol
Routes of Exposure: Eyes, skin, ingestion, inhalation
Potential Health Effects: Endocrine disruption, developmental toxicity, skin irritation, eye irritation
Precautionary Statements: Avoid breathing dust; Wash hands thoroughly after handling; Use gloves and safety goggles
Chemical Name: 19-Nor-4-Androstenediol
Concentration: >99% (analytical grade for most laboratory samples)
Impurities: Trace related steroids, solvents (residual, below 0.5%)
Stabilizers/Additives: None known
Inhalation: Move person to fresh air immediately; seek medical advice if symptoms persist; oxygen may help breathing if any shortness of breath develops
Skin Contact: Rinse affected area with plenty of water and soap for at least 15 minutes; remove contaminated clothing right away
Eye Contact: Rinse eyes continuously with water for at least 15 minutes, lifting eyelids; seek medical help if irritation stays
Ingestion: If swallowed, rinse mouth and drink water; seek medical attention promptly; never give anything by mouth to an unconscious person
Suitable Extinguishing Media: Water spray, alcohol-resistant foam, dry powder, carbon dioxide
Unsuitable Media: Direct high-pressure water jet on powders
Fire Hazards: Combustible at elevated temperatures, emits toxic fumes like carbon oxides if burning
Protective Equipment for Firefighters: Full protective gear and self-contained breathing apparatus
Special Instructions: Cool exposed containers with water spray to prevent pressure build-up or rupture
Personal Precautions: Wear gloves, safety glasses, dust mask; avoid contact with skin, eyes, clothing
Environmental Precautions: Prevent from entering water sources, soil, and drains
Cleanup Methods: Use chemical spill kit, dampen and scoop solid material, wipe area with moist absorbent, dispose of waste following regulations
Handling Advice: Handle with clean gloves and lab coat; work in well-ventilated area or inside chemical fume hood; avoid dust formation
Storage Conditions: Keep container tightly closed in a dry, cool, and well-ventilated place; store locked up, away from light, heat, and incompatible materials
Incompatibilities: Strong oxidizing agents, strong acids
Other Precautions: Keep separate from food, drink, and animal feed
Engineering Controls: Use fume hood, local exhaust ventilation
Individual Protection: Protective gloves (nitrile or latex), safety goggles, lab coat, respirator in case of dust
Hygiene Measures: Do not eat, drink, or smoke while handling; wash hands after work
Exposure Limits: No established occupational exposure limits; minimize exposure
Appearance: White or off-white crystalline solid
Odor: Odorless
Melting Point: 172 – 176°C
Boiling Point: Not available (decomposes)
Solubility: Poorly soluble in water; soluble in ethanol, DMSO, and other organic solvents
Density: Approximately 1.1 g/cm³
pH: Not applicable (solid form)
Vapor Pressure: Negligible
Partition Coefficient (log Kow): Estimated 3-4 (lipophilic)
Stability: Chemically stable under standard room conditions and recommended storage
Hazardous Reactions: No hazardous polymerization
Incompatible Materials: Oxidizers, strong acids, alkali metals
Hazardous Decomposition Products: Burns to produce carbon oxides, toxic smoke
Conditions to Avoid: Exposure to excessive heat, light, strong acids, oxidizing environments
Acute Toxicity: Not well documented; assumed low from structural analogs, but reproductive toxicity suspected
Skin Irritation: May cause mild skin irritation in prolonged contact
Eye Irritation: May cause redness, watering, or discomfort
Chronic Effects: Can alter hormone levels if absorbed repeatedly; risk for reproductive system changes
Carcinogenicity: Not classified as carcinogenic, but steroid hormones have structural similarities to known endocrine disruptors
Ecotoxicity: Data unavailable; chemical structure suggests possible aquatic toxicity, especially for fish and amphibians
Persistence and Degradability: Poorly biodegradable; steroid backbone does not degrade rapidly in typical environmental conditions
Bioaccumulative Potential: Expected to bioaccumulate in aquatic organisms due to lipophilicity
Mobility: Low in soil due to poor water solubility
Other Effects: Endocrine disruption in sensitive species possible at low concentrations
Product Disposal: Collect in sealed chemical waste container and send to licensed disposal facility
Contaminated Packaging: Rinse thoroughly then treat as hazardous waste
Environmental Precautions: Do not dispose of through sewage or municipal waste; follow local, state, and federal environmental regulations
Recommended Disposal Method: High-temperature incineration with pollution control
UN Number: Not regulated for transport
Transport Hazard Class: Not classified
Packing Group: Not applicable
Special Precautions: Keep away from direct sunlight, heat sources; transport in closed, labeled containers; provide accompanying documentation to receiver
TSCA Inventory: Not listed for specific pharmaceutical use
EU Inventory: Substance subject to restrictions under REACH for non-medical use
Other Listings: No current specific restrictions on synthesis or research but subject to sports doping regulations
Labeling: Handled as potentially hazardous chemical in laboratories according to OSHA Hazard Communication Standard or EU CLP Regulation
Workplace Regulation: Implement controls for substances causing reproductive harm; update workplace risk assessments regularly
