Product Name: 1-Androstenedione
Chemical Name: 5α-androst-1-ene-3,17-dione
CAS Number: 571-63-1
Synonyms: 1,4-Androstadiene-3,17-dione, 1-Andro
Recommended Use: Laboratory research, chemical synthesis
Supplier Details: Research Chemical Supplier, 1234 Science Drive, ChemCity, USA
Emergency Contact Number: (800) 555-0199
Email: techsupport@chemsupplier.com
Hazard Classification: Not classified as hazardous per OSHA Hazard Communication Standard (29 CFR 1910.1200)
Label Elements: No pictogram or signal word required
Health Effects: May cause hormone imbalance, skin and eye irritation
Environmental Effects: Not expected to be hazardous in normal usage, poor water solubility limits aquatic spread
GHS Signal Word: None
Hazard Statements: Potential endocrine disruption
Precautionary Statements: Avoid contact with eyes, skin, and clothing. Avoid inhalation and ingestion. Wash hands after handling.
Chemical Name: 5α-androst-1-ene-3,17-dione
Common Name: 1-Androstenedione
Purity: >98% by HPLC
Impurities: Trace androstadienedione derivatives (<2%)
Additives: None reported
Inhalation: Remove to fresh air. Seek medical attention if symptoms develop. Provide oxygen if breathing feels difficult.
Skin Contact: Remove affected clothing. Wash skin with plenty of soap and water. Seek medical advice for irritation or persistent discomfort.
Eye Contact: Rinse cautiously with water for at least 15 minutes. Remove contacts if present. Call a physician if irritation persists.
Ingestion: Rinse mouth. Do not induce vomiting. Drink water if conscious. Seek immediate medical advice.
Most Important Symptoms: Hormonal changes, mild skin/eye irritation, gastrointestinal discomfort if ingested
Suitable Extinguishing Media: Use dry chemical powder, carbon dioxide, or foam. Water spray may be used for larger fires.
Fire Hazards: Combustible as organic solid. May emit toxic fumes of carbon oxides when heated.
Special Protective Equipment: Wear self-contained breathing apparatus and full protective gear.
Advice for Firefighters: Evacuate area if fire is uncontrolled. Fight from safe distance. Prevent run-off from entering drains.
Explosion Data: No risk of explosion under normal uses. Dust buildup in air possibly explosive in confined locations.
Personal Precautions: Use personal protective equipment including gloves, safety goggles, and lab coat. Ventilate area.
Environmental Precautions: Prevent release to environment where possible. Do not let chemical enter drains or water sources.
Methods for Clean-up: Sweep up and collect spilled material into a suitable container for disposal. Clean area with detergent and water. Avoid raising dust. Dispose following local regulations.
Handling: Avoid breathing dust or vapors. Use only in well-ventilated areas. Wear personal protective equipment. Do not eat, drink, or smoke during use.
Storage: Store in tightly closed container at 2-8°C, dry conditions, away from incompatible materials like strong acids or oxidizers. Keep container clearly labeled and out of reach of unauthorized personnel.
Incompatible Materials: Strong oxidizing agents, strong acids, alkalis
Specific End Use: For research and laboratory use only, not for human consumption or drug production
Control Parameters: No occupational exposure limit established for 1-Androstenedione
Engineering Controls: Mechanical exhaust recommended for enclosed areas. Use local fume hood for significant quantities.
Personal Protective Equipment: Protective nitrile gloves, chemical safety goggles, lab coat, dust mask if airborne concentrations rise
Hygiene Measures: Wash hands immediately after use. Remove contaminated clothing and launder before reuse. Do not touch exposed skin until washed.
Environmental Exposure: Avoid release to environment. Use containment when handling bulk amounts.
Appearance: White to off-white crystalline powder
Odor: Odorless
Odor Threshold: Not determined
pH: Not applicable
Melting Point: 152–156°C
Boiling Point: Not available; degrades prior to boiling
Flash Point: Not available
Evaporation Rate: Not applicable
Flammability: Combustible solid
Upper/Lower Flammability Limits: Not established
Vapor Pressure: Negligible at room temperature
Vapor Density: Not available
Solubility: Insoluble in water; soluble in ethanol, DMSO, acetone
Partition Coefficient (Log Pow): Not available
Autoignition Temperature: Not determined
Decomposition Temperature: Not available
Viscosity: Not applicable (solid)
Chemical Stability: Stable under recommended storage conditions. Long-term exposure to light or heat may degrade material.
Possibility of Hazardous Reactions: Not likely to polymerize. Dangerous reactions may occur with strong oxidizers.
Conditions to Avoid: Heat, moisture, sunlight, incompatible chemicals
Incompatible Materials: Strong acids, oxidizing agents
Hazardous Decomposition: Carbon monoxide, carbon dioxide, possibly smoke and unidentified organic compounds
Acute Toxicity: No acute toxicity data available for humans; related steroids may cause hormone imbalance on exposure.
Irritation: May cause skin and eye irritation.
Inhalation: Dust inhalation could cause respiratory irritation.
Chronic Effects: Prolonged or repeated exposure could impact endogenous hormone production, especially with ingestion or skin absorption.
Carcinogenicity: No components listed as a carcinogen by NTP, IARC, or OSHA.
Mutagenicity: No standard mutagenicity data available.
Reproductive Toxicity: May affect reproductive system due to hormonal activity.
Ecotoxicity: Low expected aquatic toxicity based on water insolubility, but hormonal effects could impact exposed wildlife.
Persistence & Degradability: Likely to persist in environment; biodegradable over time by soil microbes.
Bioaccumulation Potential: Moderate potential for bioaccumulation in aquatic life due to low water solubility and high log Pow for similar compounds.
Mobility in Soil: Limited movement due to low solubility.
Other Adverse Effects: Unknown impact on sewage and wastewater treatment if released in significant quantity.
Waste Treatment Methods: Collect material in suitable, properly labeled containers. Dispose in accordance with federal, state, and local regulations as non-hazardous solid waste unless local rules state otherwise.
Contaminated Packaging: Rinse with water; dispose as chemical waste.
Disposal Recommendations: Use a certified chemical disposal contractor. Avoid littering or dumping into aqueous environments.
UN Number: Not classified as dangerous for transport
Transport Hazard Class: None
Packing Group: Not regulated
Marine Pollutant: No
Proper Shipping Name: Not regulated
Additional Information: Ship in sealed, labeled containers. Avoid breakage during transit.
US Regulations: Not federally scheduled as a controlled substance; always consult local legislation for updates
EU Regulations: Not registered under REACH; research use only
Canada Regulations: Not listed under WHMIS, for laboratory use only
Other Regulatory Listings: No international chemical inventory status; not subject to chemical weapon conventions or export bans for research applications
Reportable Quantities: None stated
Safety Assessment: Use and disposal should still comply with good laboratory practices and respect health guidance for novel steroidal compounds
