Product Name: 1-Androstenediol
Chemical Name: 5α-androst-1-ene-3β,17β-diol
Synonyms: 1-androstene-3β,17β-diol; 1-AD; 1-Diol
CAS Number: 571-30-8
EC Number: 209-334-9
Recommended Use: Reference chemical, research and laboratory settings
Supplier Information: Manufacturer or distributor address, contact details, and emergency phone number provided by supplier
Emergency Overview: White to off-white crystalline powder, not intended for food or drug use, regulated for handling in laboratories only
GHS Classification: Not formally classified due to limited data, but considered potentially harmful if swallowed, may irritate eyes or skin on contact
Signal Word: Caution
Hazard Statements: Possible harmful effects on reproductive system, respiratory irritation possible, dust generation could irritate upper airway, limited toxicity data warrants careful use
Pictograms: Not officially assigned, but handle as with similar hormone analogues
Precautionary Statements: Wear protective gear, avoid inhalation of powders, prevent contact with skin and eyes, do not eat, drink or smoke when using product
Chemical Identity: 1-Androstenediol
Purity: ≥97% (varies by supplier)
Impurities: Minor steroidal byproducts, trace solvents used in synthesis, not specified
Additives: None expected for research-grade material
Molecular Formula: C19H30O2
Molecular Weight: 290.44
Inhalation: Move exposed person to fresh air quickly, provide artificial respiration if breathing stops, seek medical attention if symptoms like coughing or shortness of breath develop
Skin Contact: Remove contaminated clothing, wash skin thoroughly with soap and cool water, watch for signs of persistent irritation, seek medical help for ongoing symptoms
Eye Contact: Flush eyes gently with water for a minimum of fifteen minutes, keep eyelids apart, remove contact lenses if present and easy to do, get prompt medical evaluation
Ingestion: Rinse mouth with water, do not induce vomiting unless directed by professional, give nothing by mouth if person is unconscious, seek urgent medical advice for exposure
Acute Symptoms: Eye redness, skin rash, respiratory irritation, possible hormonal effects over sustained exposure
Suitable Extinguishing Media: Carbon dioxide, dry chemical, foam, avoid direct water jets that could spread powder
Unsuitable Media: High-pressure water streams
Special Equipment: Positive pressure self-contained breathing apparatus, full protective clothing
Hazardous Combustion Products: May produce toxic fumes including carbon monoxide, carbon dioxide, and small amounts of steroid decomposition products
Fire/Explosion Risk: Fine powder could present dust explosion risk in heavy concentrations, manage dust build-up, mitigate ignition sources in storage areas
Personal Precautions: Wear NIOSH-approved respirator, laboratory gloves, protective goggles, work in well-ventilated area, prevent formation and inhalation of dust
Environmental Precautions: Block product from reaching water sources, sewer systems or soil, use containment and absorbent materials for large spills
Methods for Clean-Up: Scoop up material mechanically, avoid raising dust, dispose of waste in sealed, labeled containers, ventilate area, decontaminate surfaces with soap and water
Disposal: Handle waste as hazardous laboratory material, follow institutional guidelines for steroid hormones
Safe Handling Tips: Use chemical-resistant gloves, laboratory coat, certified biological safety cabinet or fume hood if dusting can occur, never pipette or ingest by mouth, control exposure routes
Storage Conditions: Store in cool, dry, well-ventilated locked area, keep container tightly closed and labeled, separate from acids, oxidizers, direct sunlight, and sources of ignition
Incompatible Materials: Strong oxidizers, strong acids
Special Precautions: Restrict access to trained personnel, maintain inventory tracking of hormone substances
Engineering Controls: Local exhaust ventilation, laboratory fume hood for weighing or handling appreciable quantities
Personal Protection: Nitrile or vinyl gloves, safety glasses, lab coat; disposable half-mask respirator with P100 filter under dusty conditions
Hygiene Measures: Wash hands after handling, remove protective clothing before leaving work area, avoid direct contact with body
Exposure Limits: No established OSHA, NIOSH, or ACGIH exposure limits for 1-Androstenediol; treat as potentially hazardous
Appearance: White to off-white crystalline powder
Odor: Odorless
Melting Point: Approximately 180–186°C
Boiling Point: Not available
Solubility: Insoluble in water, soluble in ethanol, chloroform, acetone
Density: Around 1.1 g/cm³
pH: Not applicable (solid compound)
Partition Coefficient (Log Pow): No published value, expected to be high due to steroid structure
Other Properties: Stable under normal lab storage, may degrade with light exposure
Chemical Stability: Keeps stability under standard storage in absence of moisture, heat, and light
Reactivity: Not expected to polymerize, no unusual reactivity
Conditions to Avoid: Elevated temperatures, humidity, strong sunlight, incompatibilities outlined above
Hazardous Decomposition Products: Carbon oxides and various organic fragments by thermal decomposition
Incompatible Materials: Oxidizing agents, strong acids
Routes of Exposure: Inhalation, skin and eye contact, ingestion
Acute Toxicity: Limited animal or human data, related hormonal compounds indicate potential for hormonal disruption, mucosal irritation
Chronic Effects: Data lacking on chronic intake, may disrupt endocrine function, risk to reproductive organs and liver with repeated exposure
Skin Sensitization: Potential for rash or dermatitis in sensitive individuals
Carcinogenicity: No IARC, NTP, or OSHA classification as carcinogen, though synthetic hormones class sometimes studied for such effects
Other Effects: Prolonged inactivity or mismanagement brings risk of hormone imbalances or metabolic shifts, care required for pregnant people or those with endocrine disorders
Ecotoxicity: Expected to pose risk to aquatic organisms if large amounts reach streams, low water solubility but potential for bioaccumulation in wildlife
Mobility: Not mobile in environment, binds to organic matter, moves minimally in soil
Persistence and Degradability: Does not rapidly degrade in environment, persistent steroid backbone
Bioaccumulative Potential: Potential for accumulation in fat of aquatic and terrestrial organisms
Other Adverse Effects: Unintended hormonal effects possible for exposed animals and humans, must minimize release outside controlled facilities
Material Disposal: Collect unused or waste material in sealed containers, label for hormone or cytotoxic waste, incinerate at authorized chemical disposal facility
Container Disposal: Rinse thoroughly, render unusable, dispose through hazardous waste contractor
Special Requirements: Do not discard down normal drain or with household garbage, never allow into sewers or outdoor soil, keep records for regulated disposal
Additional Information: Follow local, regional, and institutional rules regarding controlled substances and lab chemicals
UN Number: Not assigned for 1-Androstenediol
Proper Shipping Name: Laboratory chemical, not otherwise specified
Transport Hazard Class: Generally treated as nonhazardous for transport, though institutional rules may vary
Packing Group: Not assigned
Special Precautions for User: Ensure containers are well-sealed, clearly labeled, hand over shipments only to approved couriers specializing in lab goods, include MSDS with shipment
US Federal Rules: Not FDA approved for human or veterinary use, subject to controlled substance status in some states, OSHA requirements for hazard communication apply
International Status: Controlled or restricted in many countries under doping, hormone, or prescription drug laws
Workplace Labels: Mark as research chemical and potential endocrine disruptor, restrict access to authorized users
Other Rules: Ensure purchase, storage, and use meet institutional ethical and safety board requirements, keep documentation for regulatory reviews, check for annual regulatory updates as substance status may change
