4-Fluoro-3-Methoxybenzonitrile comes with some punchy chemistry. Molecular formula reads out as C8H6FNO, and the CAS number points to 654-70-6. You’ll spot it as a pale crystalline powder, carrying a molecular weight of 151.14 g/mol. Structure-wise, this benzonitrile derivative packs a fluorine at the 4-position and a methoxy group at the 3-position, which pivots its reactivity into a handy option for both pharma and agrochemical sectors.
This compound stands up well in organic synthesis due to the robust electron-withdrawing power from nitrile, paired with the unique push-and-pull of methoxy and fluorine groups. Such characteristics end up steering reactions for constructing intricate molecular scaffolds. Specific density clocks in around 1.21 g/cm³ and boiling point sits above 265°C, making it stable enough for multi-step processes that require high purity. The melting point, typically 67-69°C, sits nicely for controlled crystallization and storage. Water solubility remains low, which often helps during product isolation stages.
In my work with chemical raw materials, there’s a clear pattern: the best-performing intermediates make solid building blocks. 4-Fluoro-3-Methoxybenzonitrile supports that idea—its core fits for active molecule synthesis, custom polymer production, and specialty herbicide development. Pharmaceutical manufacturers look for such raw materials, especially when targeting advanced heterocyclic rings or specific fluorinated drugs. Demand from research labs and process development centers testifies to its consistent performance.
Considering supply, factories across China consistently offer robust manufacturing capacity and competitive factory prices. Major suppliers in the region back up every batch with MSDS, REACH, and ISO certification, which means data on safe-use and regulatory alignment stays transparent. Hazard and harmful material listings with each pack ensure handling stays compliant—my own ordering experience shows shipping partners sticking to CIF, FOB, or even DDP incoterms, which makes a difference for buyers managing budget and timeline.
The low solubility in water and moderate hazard class underscore the need for proper labeling—handling this as a raw material requires gloves, goggles, and well-ventilated workspaces. Reach out to suppliers for updated SDS and TDS sheets at time of purchase; they reflect latest safety and storage policies. Larger customers like to ask about REACH, ISO, SGS, or HALAL and KOSHER certificates, especially for regulated industries and export markets. OEM options are on the table—custom labeling and bulk packaging down to customer spec smooth out logistics during material qualification.
Quotes land fast—submit an inquiry through the supplier site, detail expected MOQ, and request free samples if needed. Pricing shifts with quantity, real-time raw material costs, and market changes, so early negotiation helps. Quotes usually come CIF or FOB; detailed MSDS and COAs always tag along. Watch policy updates regarding EU and Asia-Pacific import rules, especially for products classed as precursor chemicals. Genuine suppliers make purchase news visible, disclose current stock status, and flag policy shifts right on their homepage.
Consuming industries rely on supplier openness, especially around molecular property data, hazard identification, and regulatory proof. Whether you’re running an R&D batch or a full-scale synthesis, 4-Fluoro-3-Methoxybenzonitrile gets the job done when details matter—from HS-Code (2926909090) for customs clearance, to detailed OEM certification for downstream compliance, to practical shipment handling through stable logistics. Buyers who check the full scope—from MSDS to certification—know what arrives matches spec, budget, and regulatory need, keeping processes safe and results predictable.
