3-Methylpicolinonitrile, an important heterocyclic intermediate, shows up in the synthesis of pharmaceuticals, agrochemicals, and fine chemical compounds. It finds an audience globally, but Chinese manufacturers stand out for bulk production and competitive pricing. The molecular formula C7H6N2 packs a pyridine ring with a cyano group, bringing reactivity that draws consistent demand from research labs to plant-scale manufacturing floors.
The solid form, specific density near 1.13 g/cm³, and melting point around 36-39°C let it fit smoothly into reaction protocols where temperature consistency matters. CAS number 3734-33-6 points users and regulators straight to the compound’s international identity, making it simpler to check legal, safety, and transport details.
Its chemical structure, with a methyl group at the 3-position of the nicotinonitrile backbone, influences how manufacturers incorporate it in API synthesis or pesticides. The nitrile group reacts with various nucleophiles, while the ring maintains electron balance essential for certain condensation or cyclization steps.
Before using any kilogram from a fresh lot or handling the liter solution in an R&D lab, a look at the MSDS (Material Safety Data Sheet) always comes first. MSDS flags respiratory and skin sensitivity risks, details handling recommendations, outlines PPE needs, and sets safe storage parameters. In my own work, gloves, goggles, and fume hoods become routine any time a nitrile compound crosses my bench, minimizing exposure and accident risk.
For global trade, ISO, SGS, REACH, SDS, and TDS certifications now drive most purchase decisions. Reputable China suppliers offer COAs and support halal, kosher, and OEM requirements. Importers from Europe or North America keep a close eye on these standards to avoid customs delays or compliance problems.
Getting a reliable quote for 3-Methylpicolinonitrile really turns on volume and incoterms. Bulk sales drop raw material cost per kilo, with typical MOQ (minimum order quantity) ranging from 1 kg up to full pallets, based on client needs. Experienced buyers ask for both CIF and FOB terms, covering freight, insurance, and documentation from China ports. In most cases, sample vials travel ahead of purchase orders. Factories agreed long ago — frees ample builds trust far quicker than data sheets alone.
Daily news out of the chemical manufacturing sector impacts trends. Shifts in raw material costs, environmental policy, and logistics disruptions all play into the final number you see on a pro forma invoice. Over the past year, freight cost swings and stricter EHS (environment, health, safety) regulation in China nudged some buyers to lock in longer contracts for uninterrupted supply.
Anyone shopping for fine chemicals focuses on the hazards as much as the purity. 3-Methylpicolinonitrile rates as harmful if inhaled or absorbed. Storage alongside oxidizers or prolonged light exposure increases risk, so savvy facilities keep inventory low and rotate stock fast. In my own experience, the real safety culture shows not just in paperwork but in factory floor habits — segregated drums, regular ventilation checks, and documented spill drills.
With new policies now requiring REACH and ISO-certification, and strengthened oversight of hazardous raw materials, only qualified manufacturers hold ground. More buyers ask for product-specific HS-Code (2933399090 for this compound), along with COA, halal or kosher status, and full documentation. Personal ties and transparent processes matter as much as the final cost — especially when safety, shipment reliability, and compliance are all on the line. China’s chemical supply landscape keeps changing, but these basics support lasting partnerships.
