Every chemist scanning supply catalogs for specialty intermediates likely comes across 3,4,5-Trimethoxybenzonitrile. The chemical formula C10H11NO3 gives a solid foundation for any synthetic chemist or purchasing manager looking for a versatile benzene derivative. Its structure—bearing three methoxy groups attached to a benzonitrile core—creates unique reactivity and solubility, making it useful in pharmaceuticals, dyes, and certain polymer materials.
China stands out as the primary manufacturing base for this raw material. Most exporters provide up-to-date MSDS and TDS for compliance with global requirements, a necessity for my own projects over the years. Key terms in the trade include ISO, SGS, OEM, Halal, and Kosher certification—these carry real meaning for buyers, especially those serving diverse or multinational customers. As a rule, always check for these badges rather than just taking a supplier’s word on quality. The REACH compliance sticker also opens doors to European clients.
My experience talking price with Chinese factories highlights the typical CIF and FOB arrangements, especially for global buyers. The HS Code for 3,4,5-Trimethoxybenzonitrile generally falls under 2926909090, classifying it among organic nitriles. Pricing shifts with raw material volatility, especially methoxy precursors. For most buyers, a standard MOQ—usually around 25 kg or 100 kg—keeps costs accessible. Many suppliers offer free samples for qualified inquiries. A legitimate supplier won’t hide behind vague answers or delay shipping a small quantity for evaluation. Market news and policy bulletins published by major chemical traders offer insights, but a direct inquiry often reveals more about actual inventory and willingness to negotiate on MOQ.
Specification sheets show melting points between 70-73°C with a specific density of roughly 1.19 g/cm3. A pale yellow or off-white powder marks a typical shipment. Common solutions use acetone or DMF, with extraordinary care needed during handling: 3,4,5-Trimethoxybenzonitrile qualifies as hazardous based on GHS criteria. My team always stresses gloves, goggles, and pulse-quick safety checks as the bare essentials. The SDS covers details on inhalation hazards and proper storage, critical for anyone storing drums in a crowded warehouse. Industry best practice requires a signed document acknowledging safe handling, especially when exporting under strict customs guidelines.
Pharmaceutical researchers and industrial buyers make up the biggest demand pools. I’ve seen it feeding both lab-scale and ton-scale synthesis of bioactive materials. The product’s chemical stability and selectivity drive repeated purchases. Recent policy also tightens oversight on harmful raw materials, influenced by government efforts to regulate the flow of precursor chemicals—another reason verified suppliers, not trading companies, become crucial. For many, partnering with certified factories offering ISO or GMP documentation trims real risk from the procurement process. Buyers using this intermediate in end-products headed for the EU or North America need clear records of halal or kosher compliance now more than ever.
Chemical procurement in today’s marketplace calls for more than a good price. Buyers succeed by insisting on real documentation, current MSDS, and open supplier conversations. Comparing offers with a side-by-side review, including certification, helps eliminate trouble later. If you’re thinking about a large contract, it's wise to visit factories or use an SGS third-party inspection to confirm raw material integrity and packaging standards. Direct OEM manufacturing sometimes supports custom particle size or special packing needs—the mark of a flexible, experienced supplier. In the end, a transparent purchase process—covering quote, MOQ, CIF and FOB shipping—brings peace of mind and keeps projects moving forward.
